Palmitoylethanolamide is a disease-modifying agent in peripheral neuropathy : pain relief and neuroprotection share a PPAR-alpha-mediated mechanism [PDF]
, 2013 Peer reviewedPublisher ...
Calignano, A +6 more
core +4 more sources
Inhibitor of DNA binding 2 accelerates nerve regeneration after sciatic nerve injury in mice
Neural Regeneration Research, 2021 Inhibitor of DNA binding 2 (Id2) can promote axonal regeneration after injury of the central nervous system. However, whether Id2 can promote axonal regeneration and functional recovery after peripheral nerve injury is currently unknown.
Zhong-Hai Huang +5 more
doaj +1 more source
Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury. [PDF]
, 2018 BACKGROUND:In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after ...
Angert, Mila +6 more
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Thrombin regulates the ability of Schwann cells to support neuritogenesis and to maintain the integrity of the nodes of Ranvier [PDF]
, 2020 Schwann cells (SC) are characterized by a remarkable plasticity that enables them to promptly respond to nerve injury promoting axonal regeneration. In peripheral nerves after damage SC convert to a repair-promoting phenotype activating a sequence of ...
Ciraci, Viviana +9 more
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Immune cell distribution and immunoglobulin levels change following sciatic nerve injury in a rat model [PDF]
Iranian Journal of Basic Medical Sciences, 2016 Objective(s): To investigate the systemic and local immune status of two surgical rat models of sciatic nerve injury, a crushed sciatic nerve, and a sciatic nerve transection Materials and Methods:Twenty-four adult male Sprague-Dawley rats were randomly ...
Wei Yuan, Xinhong Feng
doaj
Neural Regeneration Research, 2015 The transient receptor potential cation channel subfamily V member 1 (TRPV1) provides the sensation of pain (nociception). However, it remains unknown whether TRPV1 is activated after peripheral nerve injury, or whether activation of TRPV1 affects neural
Fei Ren +5 more
doaj +1 more source
A study of high division of sciatic nerve in human cadavers and its clinical significance
National Journal of Physiology, Pharmacy and Pharmacology, 2023 Background: Sciatic nerve is a mixed nerve which provide sensory and motor supply for skin and muscles of the lower limb by tibial and common peroneal nerve.
Mayuri P Shah +2 more
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Dexamethasone prevents vascular damage in early-stage non-freezing cold injury of the sciatic nerve
Neural Regeneration Research, 2016 Non-freezing cold injury is a prevalent cause of peripheral nerve damage, but its pathogenic mechanism is poorly understood, and treatment remains inadequate. Glucocorticoids have anti-inflammatory and lipid peroxidation-inhibiting properties.
Hao Li, Lei Zhang, Min Xu
doaj +1 more source
Progranulin contributes to endogenous mechanisms of pain defense after nerve injury in mice [PDF]
, 2012 Progranulin haploinsufficiency is associated with frontotemporal dementia in humans. Deficiency of progranulin led to exaggerated inflammation and premature aging in mice.
Albuquerque, Boris +5 more
core +1 more source
Sciatic Nerve Injury Associated with Acetabular Fractures [PDF]
HSS Journal®: The Musculoskeletal Journal of Hospital for Special Surgery, 2009 Sciatic nerve injuries associated with acetabular fractures may be a result of the initial trauma or injury at the time of surgical reconstruction. Patients may present with a broad range of symptoms ranging from radiculopathy to foot drop. There are several posttraumatic, perioperative, and postoperative causes for sciatic nerve palsy including ...
Paul S, Issack, David L, Helfet
openaire +2 more sources