Results 41 to 50 of about 56,654 (252)

Temporal changes in the spinal cord transcriptome after peripheral nerve injury

open access: yesNeural Regeneration Research, 2020
Peripheral nerve injury may trigger changes in mRNA levels in the spinal cord. Finding key mRNAs is important for improving repair after nerve injury. This study aimed to investigate changes in mRNAs in the spinal cord following sciatic nerve injury by ...
Jian Weng   +3 more
doaj   +1 more source

The NMDA receptor functions independently and as an LRP1 co-receptor to promote Schwann cell survival and migration [PDF]

open access: yes, 2015
NMDA Receptors (NMDA-Rs) are ionotropic glutamate receptors, which associate with LDL Receptor-related Protein-1 (LRP1) to trigger cell-signaling in response to protein ligands in neurons.
Campana, W. Marie   +4 more
core   +2 more sources

Combination therapy using evening primrose oil and electrical stimulation to improve nerve function following a crush injury of sciatic nerve in male rats

open access: yesNeural Regeneration Research, 2017
Peripheral nerve injuries with a poor prognosis are common. Evening primrose oil (EPO) has beneficial biological effects and immunomodulatory properties.
Omid Badri   +6 more
doaj   +1 more source

Nerve damage induced skeletal muscle atrophy is associated with increased accumulation of intramuscular glucose and polyol pathway intermediates [PDF]

open access: yes, 2020
Perturbations in skeletal muscle metabolism have been reported for a variety of neuromuscular diseases. However, the role of metabolism after constriction injury to a nerve and the associated muscle atrophy is unclear.
Afzal, Shoaib   +3 more
core   +2 more sources

Brain injury in combination with tacrolimus promotes the regeneration of injured peripheral nerves

open access: yesNeural Regeneration Research, 2017
Both brain injury and tacrolimus have been reported to promote the regeneration of injured peripheral nerves. In this study, before transection of rat sciatic nerve, moderate brain contusion was (or was not) induced.
Xin-ze He   +8 more
doaj   +1 more source

Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury. [PDF]

open access: yes, 2009
A principal objective of spinal cord injury (SCI) research is the restoration of axonal connectivity to denervated targets. We tested the hypothesis that chemotropic mechanisms would guide regenerating spinal cord axons to appropriate brainstem targets ...
Alto, Laura Taylor   +5 more
core   +2 more sources

Baculoviral inhibitor of apoptosis protein repeat-containing protein 3 delays early Wallerian degeneration after sciatic nerve injury

open access: yesNeural Regeneration Research, 2022
Wallerian degeneration is a complex biological process that occurs after nerve injury, and involves nerve degeneration and regeneration. Schwann cells play a crucial role in the cellular and molecular events of Wallerian degeneration of the peripheral ...
Min Cai   +8 more
doaj   +1 more source

Transcript expression of vesicular glutamate transporters in lumbar dorsal root ganglia and the spinal cord of mice – Effects of peripheral axotomy or hindpaw inflammation [PDF]

open access: yes, 2013
Using specific riboprobes, we characterized the expression of vesicular glutamate transporter (VGLUT)1–VGLUT3 transcripts in lumbar 4–5 (L4–5) dorsal root ganglions (DRGs) and the thoracolumbar to lumbosacral spinal cord in male BALB/c mice after a 1- or
Brumovsky, Pablo Rodolfo   +8 more
core   +1 more source

Investigation for the correlation between brain injury and injured ipsilateral sciatic nerve regeneration in a rat model

open access: yesJournal of Integrative Neuroscience, 2019
Previous studies showed that brain trauma promotes repair of peripheral nerve injury by reducing scar in nerve endings. The effect of brain injury at different locations on ipsilateral rat sciatic nerve regeneration in Sprague-Dawley rats was found to ...
Haoqi Wang   +5 more
doaj   +1 more source

Saikosaponin a increases interleukin-10 expression and inhibits scar formation after sciatic nerve injury

open access: yesNeural Regeneration Research, 2018
Nerve scarring after peripheral nerve injury can severely hamper nerve regeneration and functional recovery. Further, the anti-inflammatory cytokine, interleukin-10, can inhibit nerve scar formation.
Meng-Qiang Huang   +9 more
doaj   +1 more source

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