Results 101 to 110 of about 58,051 (308)

Noninvasive electrodiagnostic and motor function assessment of the common fibular nerve regeneration in the rabbit hindlimb

Animal Models and Experimental Medicine, EarlyView.
The rabbit model is well‐suited for peripheral nerve repair studies, using electrodiagnostic testing as an effective and reliable technique for fibular nerve regeneration evaluation, combined with motor function assessment using the toe spread index.
Olivier Larrivée, Alexane Thibodeau, Rosemarie Rinfret‐Paquet, Todd Galbraith, Oumayma Hayouni, Hélène T. Khuong, François Berthod   +6 more
wiley   +1 more source

Recombinant Human Neuregulin1‐β1 Significantly Reduces Schwannoma Growth in Mice

Annals of Neurology, EarlyView.
rhNRGβ1‐Replacement‐Therapy: Under physiological conditions, NRGβ1 is expressed on axons (in orange), where it activates ERBB2 receptors, facilitating successful nerve regeneration following injury. However, loss of NF2 leads to a reduction in NRGβ1‐expression and increased ErbB2 levels on Schwann cells (in green), which contributes to schwannoma ...
Julia P. Bischoff, Alexander Schulz, Christian Hagel, Robert Büttner, Michael Reuter, Waylan K. Bessler, D. Wade Clapp, Helen Morrison   +7 more
wiley   +1 more source

miR-30c promotes Schwann cell remyelination following peripheral nerve injury

Neural Regeneration Research, 2017
Differential expression of miRNAs occurs in injured proximal nerve stumps and includes miRNAs that are firstly down-regulated and then gradually up-regulated following nerve injury. These miRNAs might be related to a Schwann cell phenotypic switch.
Sheng Yi, Qi-hui Wang, Li-li Zhao, Jing Qin, Ya-xian Wang, Bin Yu, Song-lin Zhou   +6 more
doaj   +1 more source

Sciatic Nerve Palsy following Curved Periacetabular Osteotomy

Case Reports in Orthopedics, 2020
Curved periacetabular osteotomy (CPO) is used for the treatment of dysplastic hips. Previous studies have reported satisfying outcomes and low rate of severe complications associated with this procedure; however, no case of postoperative sciatic nerve ...
Masahiro Fujita, Shinya Hayashi, Kenichi Kikuchi, Yoshinori Takashima, Tomoyuki Kamenaga, Masanori Tsubosaka, Koji Fukuda, Koji Takayama, Shingo Hashimoto, Takahiro Niikura, Ryosuke Kuroda, Tomoyuki Matsumoto   +11 more
doaj   +1 more source

An examination of walking track analysis footprints of right-side unoperated limbs in rats prior to and following peripheral nerve injury and PEG fusion repair [PDF]

, 2018
Peripheral nerve injury can result in long-lasting functional deficits in humans due to mammals’ limited axon regenerative capacity. PEG fusion is a defined technique that fuses injured axons, resulting in morphological and electrophysiological ...
Jagannath, Karthik
core   +1 more source

The Functional Results of Acute Nerve Grafting in Traumatic Sciatic Nerve Injuries

Turkish Journal of Trauma and Emergency Surgery, 2013
The sciatic and peroneal nerves are the most frequently injured in lower extremities, followed by tibial and femoral nerves. The aim of this study is to evaluate the functional results of acute nerve grafting in traumatic sciatic nerve injuries.A total of 9 patients with sciatic nerve defect were treated with primary nerve grafting. The mean age was 31.
Karaca, Can, VAYVADA, HALUK, DEMİRDÖVER, CENK, YILMAZ, MUSTAFA, MENDERES, ADNAN   +4 more
openaire   +4 more sources

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic pain [PDF]

, 2017
Background: L-acetylcarnitine, a drug marketed for the treatment of chronic pain, causes analgesia by epigenetically up-regulating type-2 metabotropic glutamate (mGlu2) receptors in the spinal cord.
Battaglia, Giuseppe, Bernabucci, Matteo, Bruno, Valeria Maria Gloria, Cannella, Milena, Gradini, Roberto, Imbriglio, Tiziana, Mascio, Giada, Nicoletti, Ferdinando, Notartomaso, Serena, Scarselli, Pamela, Zappulla, Cristina   +10 more
core   +1 more source

Bioprinted Excitable Tissues with Multistimulation Systems for Promoting Function and Maturation

Advanced NanoBiomed Research, EarlyView.
This review provides an overview of stimulation strategies used to enhance the functional maturation of bioprinted excitable tissues. It addresses key limitations in physiological performance of bioprinted excitable tissues, outlines major stimulation modalities—including electrical, mechanical, optical, magnetic, ultrasound, and hybrid—and examines ...
Uijung Yong, Jinseon Park, Jinah Jang
wiley   +1 more source

Dysregulation of NAD+ metabolism induces a Schwann cell dedifferentiation program [PDF]

, 2018
The Schwann cell (SC) is the major component of the peripheral nervous system (PNS) that provides metabolic and functional support for peripheral axons. The emerging roles of SC mitochondrial function for PNS development and axonal stability indicate the
Hackett, Amber R, Kim, Sungsu, Milbrandt, Jeffrey, Sasaki, Yo, Strickland, Amy   +4 more
core   +1 more source