Results 21 to 30 of about 58,051 (308)

Robust temporal changes of cellular senescence and proliferation after sciatic nerve injury

open access: yesNeural Regeneration Research, 2022
Cellular senescence and proliferation are essential for wound healing and tissue remodeling. However, senescence-proliferation cell fate after peripheral nerve injury has not been clearly revealed.
Yin-Ying Shen   +4 more
doaj   +1 more source

Combat Injury of the Sciatic Nerve – An Institutional Experience [PDF]

open access: yesMilitary Medicine, 2018
Combat injury of the sciatic nerve tends to be severe with variable but often profound consequences, is often associated with widespread soft tissue and bone injuries, significant neurologic impairment, severe neuropathic pain, and a prolonged recovery time.
Patrick E, Jones   +6 more
openaire   +5 more sources

Silencing of circRNA.2837 Plays a Protective Role in Sciatic Nerve Injury by Sponging the miR-34 Family via Regulating Neuronal Autophagy

open access: yesMolecular Therapy: Nucleic Acids, 2018
Circular RNAs (circRNAs) represent a class of non-coding RNAs that are involved in transcriptional and posttranscriptional gene expression regulation and associated with different kinds of human diseases.
Zhi-bin Zhou   +5 more
doaj   +1 more source

Interfacing peripheral nerve with macro-sieve electrodes following spinal cord injury [PDF]

open access: yes, 2017
Macro-sieve electrodes were implanted in the sciatic nerve of five adult male Lewis rats following spinal cord injury to assess the ability of the macro-sieve electrode to interface regenerated peripheral nerve fibers post-spinal cord injury. Each spinal
Birenbaum, Nathan K   +2 more
core   +3 more sources

Enhancement of sciatic nerve regeneration with dual delivery of vascular endothelial growth factor and nerve growth factor genes

open access: yesJournal of Nanobiotechnology, 2020
Background Peripheral nerve injury is one common clinical disease worldwide, in which sciatic nerve is anatomically the most challenging to regenerate given its length and large cross-sectional area.
Zhiwei Fang   +5 more
doaj   +1 more source

Dexmedetomidine Improves Locomotor Function and Alleviates Thermal Hyperalgesia Following Sciatic Nerve Crush Injury in Rats [PDF]

open access: yesInternational Neurourology Journal, 2020
Purpose The effects of dexmedetomidine on locomotor function and thermal hyperalgesia in sciatic nerve crush injury (SNCI) were investigated using rats.
Myung-Soo Jang   +7 more
doaj   +1 more source

Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes [PDF]

open access: yes, 2015
Background: NOD-like receptors (Nlrs) are key regulators of immune responses during infection and autoimmunity. A subset of Nlrs assembles inflammasomes, molecular platforms that are activated in response to endogenous danger and microbial ligands and ...
De Winter, Vicky   +6 more
core   +2 more sources

Bone marrow-derived mesenchymal stem cells versus adipose-derived mesenchymal stem cells for peripheral nerve regeneration

open access: yesNeural Regeneration Research, 2018
Studies have confirmed that bone marrow-derived mesenchymal stem cells (MSCs) can be used for treatment of several nervous system diseases. However, isolation of bone marrow-derived MSCs (BMSCs) is an invasive and painful process and the yield is very ...
Marcela Fernandes   +7 more
doaj   +1 more source

Evaluation methods of a rat sciatic nerve crush injury model

open access: yesJournal of Integrative Neuroscience, 2022
Background: The rat sciatic nerve crush injury model is one of the most commonly used models to research peripheral nerve injury (PNI), however, the evaluation of the model preparation lacks exact standards.
Yun An   +4 more
doaj   +1 more source

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