Results 71 to 80 of about 58,051 (308)

Glial βii spectrin contributes to paranode formation and maintenance [PDF]

, 2018
Action potential conduction along myelinated axons depends on high densities of voltage-gated Na channels at the nodes of Ranvier. Flanking each node, paranodal junctions (paranodes) are formed between axons and Schwann cells in the peripheral nervous ...
Benusa, Savannah D., Chang, Kae Jiun, Dupree, Jeffrey L., Galiano, Mauricio Raul, Griggs, Ryan B., Huang, Claire Yu Mei, Liu, Yanhong, Rasband, Matthew N., Susuki, Keiichiro, Tsai, Chang Ru, Yermakov, Leonid M., Zhang, Chuansheng, Zollinger, Daniel R.   +12 more
core   +1 more source

Self‐Assembling Peptide Hydrogels Support Stromal Vascular Fraction Viability to Promote In Vivo Nerve Regeneration

Advanced Healthcare Materials, EarlyView.
Stromal vascular fraction (SVF) may enhance nerve repair, especially when delivered in a self‐assembling peptide hydrogel (SAPH). In vitro, softer SAPH increased neuronal explant outgrowth and supported greater SVF viability and proliferation. In a rat sciatic defect, SVF in an optimized SAPH produced motor and sensory recovery equivalent to autograft ...
Liam A. McMorrow, Steffan Llewellyn, Jared McSweeney, Alessandro Faroni, Aline F. Miller, Alberto Saiani, Adam J. Reid   +6 more
wiley   +1 more source

Electrophysiological Evaluation of a Sciatic Nerve Degree III Injury Model in Rats

Bio-Protocol
Sciatic nerve injury is a prevalent traumatic condition that significantly impacts a patient's quality of life. The sciatic nerve compression injury model is among the most commonly utilized models for investigating nerve repair and regeneration ...
Linyu Chen, Ziyi Wang, Chengyao Wang, Ning Ma, Weiqin Zhao, Shuang Liu, Jiajun Lu, Boyuan Zhao, Hong Sun, Pengcheng Che, Na Dou   +10 more
doaj   +1 more source

Bacterial melanin promotes recovery after sciatic nerve injury in rats

Neural Regeneration Research, 2015
Bacterial melanin, obtained from the mutant strain of Bacillus Thuringiensis, has been shown to promote recovery after central nervous system injury. It is hypothesized, in this study, that bacterial melanin can promote structural and functional recovery
Olga V Gevorkyan, Irina B Meliksetyan, Tigran R Petrosyan, Anichka S Hovsepyan   +3 more
doaj   +1 more source

Artificial PGA/Collagen-based Bilayer Conduit in Short Gap Interposition Setting Provides Comparable Regenerative Potential to Direct Suture

Plastic and Reconstructive Surgery, Global Open, 2023
Background:. The aim of this study was to evaluate whether the Nerbridge, an artificial polyglycolic acid conduit with collagen matrix, is comparable to direct nerve suture in a rat sciatic nerve injury model in a short-gap interposition (SGI) setting ...
Yu Li, MD, Keisuke Takanari, MD, PhD, Ryota Nakamura, MD, PhD, Miki Kambe, MD, Katsumi Ebisawa, MD, PhD, Mayumi Oishi, MD, Yuzuru Kamei, MD, PhD   +6 more
doaj   +1 more source

The Space Within: How Architected Voids Promote Tissue Formation

Advanced Materials, EarlyView.
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou, Isabel B. Hui, Carla Fernandez‐Rico, Marcy Zenobi‐Wong   +3 more
wiley   +1 more source

Mild Mechanic Stimulate on Acupoints Regulation of CGRP-Positive Cells and Microglia Morphology in Spinal Cord of Sciatic Nerve Injured Rats

Frontiers in Integrative Neuroscience, 2019
ObjectiveThe objective of this study is to observe the effects of mild mechanical stimulation on acupuncture points of spinal motor neurons and active substances of sciatic nerve injury in rats, and to explore the morphological basis for the recovery of ...
Li Yi-zhen, Miao Run-pei, Yu Tian-yuan, Bai Wan-zhu, Cui Jing-jing, Lu Meng-qian, Shen Yi, Luo Yu-ting, Shao Shuai, Zhang Yu-mo, Mo Yan-jun, Lv Tao-tao, Chen Guo-yong   +12 more
doaj   +1 more source

Biomimetic chitosan scaffolds with long-term controlled release of nerve growth factor repairs 20-mm-long sciatic nerve defects in rats

Neural Regeneration Research, 2022
Although autogenous nerve transplantation is the gold standard for treating peripheral nerve defects of considerable length, it still has some shortcomings, such as insufficient donors and secondary injury.
Fa-Dong Liu, Hong-Mei Duan, Fei Hao, Wen Zhao, Yu-Dan Gao, Peng Hao, Zhao-Yang Yang, Xiao-Guang Li   +7 more
doaj   +1 more source

Bilateral variant of sciatic nerve exhibiting intra-pelvic division [PDF]

, 2014
Context (background): In case of high division of the sciatic nerve in the pelvis its, common peroneal component may pierce the Piriformis muscle. This anatomical variant can explain many clinical findings. Aims: Its objective is to report a case of high
Rejeena P Raj, Kunjumon PC, More Anju B
core   +1 more source

Galvanic‐Cell‐Based Self‐Powered Bioelectronic Devices

Advanced Materials, EarlyView.
The emerging galvanic‐cell‐based self‐powered bioelectronics for biomedical applications with passive and active control strategies are summarized. In addition, the challenges and opportunities for galvanic devices are also discussed. Abstract Bioelectronic devices hold significant promise for advancing biomedical technologies, addressing critical ...
Yu Xin, Longfei Chen, Bin Sun, Fangping Tang, Yamin Zhang   +4 more
wiley   +1 more source