Results 111 to 120 of about 51,210 (327)

Effect and neurophysiological mechanism of acupuncture in patients with chronic sciatica: protocol for a randomized, patient-assessor blind, sham-controlled clinical trial

open access: yesTrials, 2019
BackgroundSciatica is a relatively frequent illness that easily becomes a chronic and relapsing condition. Although numerous systematic reviews have analyzed various therapies for sciatica, the validity of their included studies is limited.
Koh-Woon Kim   +11 more
semanticscholar   +1 more source

Diosgenin ameliorates silica‐induced tuberculosis in rats

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Silicosis increases susceptibility to tuberculosis due to impaired macrophage function and oxidative stress. This study demonstrates that diosgenin, a steroidal saponin, significantly inhibits Mycobacterium smegmatis (IC₅₀ = 0.006 μg/mL), reduces lung fibrosis, and restores antioxidant enzyme levels (↑SOD, ↑CAT, ↓MDA) in silica‐exposed rats ...
Williams Asamoah Adu   +5 more
wiley   +1 more source

THE RATIONAL TREATMENT OF SCIATICA [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1890
n ...
openaire   +3 more sources

Development, validation, and preliminary phenotypic characterization of a Col6a3 knockout mouse model targeting exon 3

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Deleting Col6a3 exon 3 by CRISPR in mice results in centralized nuclei consistent with a myopathy phenotype mimicking collagen VI‐associated human disease Abstract Background Most mutations in the COL6A3 gene lead to collagen VI‐related myopathies. This is due to a reduced expression or mislocalization of the COL6A3 protein.
Michel ElChoueiry   +12 more
wiley   +1 more source

Toward Natural Limb Function: A New Era in Prosthetic Innovation

open access: yesAnnals of Neurology, EarlyView.
The past decade has witnessed groundbreaking clinical implementation of neuroprosthetic limbs driven by signals from peripheral targets (eg, nerves and muscle) and the brain to restore limb function for individuals with limb loss or impairment. In this review, we highlight recent key clinical trials in peripheral neuroprosthetic interfaces directly ...
Yucheng Tian   +4 more
wiley   +1 more source

When is discectomy indicated for lumbar disc disease? [PDF]

open access: yes, 2011
Emergent discectomy is indicated in the presence of cauda equina and severe, progressive neuromotor deficits (strength of recommendation [SOR]: C, expert opinion).
Brown, Rhett   +3 more
core  

Towards Polymer Composite‐Based Transient Electronic Systems

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biodegradable electronic systems are gaining attention for implantable biomedical applications, targeting disease treatment and lifespan extension. This review covers advances in biocompatible, biodegradable polymer composites using synthetic and natural polymers with conductive, semiconductive, and insulating fillers.
Gwan‐Jin Ko   +5 more
wiley   +1 more source

Cationic Nanoparticles Mitigate Chemotherapy‐Induced Peripheral Neuropathy

open access: yesAdvanced NanoBiomed Research, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN), caused by chemodrugs like paclitaxel (PTX), leads to severe neuropathic pain. This study evaluates PTX‐loaded PAMAM‐Chol nanoparticles (PTX‐NPs) to alleviate CIPN. PTX‐NPs achieve 99% drug‐loading efficiency, reduce neurotoxicity, and in murine models, decrease cold allodynia by 85% while restoring ...
Divya Bhansali   +7 more
wiley   +1 more source

Steroid For Management Of Pseudo-othematoma [PDF]

open access: yes, 2011
Has conducted research on the use of steroids triamsinolon asetonid as pseudo-othematomamedical therapy. The purpose of this study was to determine the effectiveness triamsinolonasetonid. Prevention of the formation of serum in the lesion, so that pseudo-
Adiputra, N. (Nyoman)   +2 more
core  

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