Results 161 to 170 of about 47,052 (316)

LPC18:0 Secreted by Exogenous Neural Stem Cells Potentiates Neurogenesis and Functional Recovery via GPR55‐Mediated Signalling in Spinal Cord Injury

Cell Proliferation, EarlyView.
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen, Shuo Liu, Le‐Yi Tu, Ming‐Mei Yang, Cong‐Wang Xu, Yue Jiang, Hui Yang, Chen‐Xu Tai, Yan‐Ning Wang, Yuan‐Yuan Xie, Ping‐Ping Shen, Bin Wang   +11 more
wiley   +1 more source

Propionibacterium acnes evades microbicidal phagocytosis by inhibiting the mitochondrial biogenesis of nucleus pulposus cells

The FEBS Journal, EarlyView.
P. acnes infection impairs the mitochondrial biogenesis of nucleus pulposus cells (NPCs) through the AMPK/SIRT‐1/PGC‐1α signaling pathway. This results in impaired mitochondria that are unable to generate sufficient ATP, and impaired delivery of mitochondrial reactive oxygen species to carry out the bactericidal process effectively.
Lemeng Ren, Changwei Li, Juntao Sun, Yuehuan Zheng, Yucheng Jiao, Jiancheng Zheng, Fangke Zhang, Yazhou Lin, Wenjian Wu, Peng Cao   +9 more
wiley   +1 more source

Causal effect of education on low back pain, intervertebral disc degeneration and sciatica: Mendelian randomization study. [PDF]

Future Sci OA
Wu Z, Gong Y, Long H, Deng R, He J, Su M, Wang J, Gong K.   +7 more
europepmc   +1 more source

Low back pain and radicular pain : assessment and management [PDF]

, 2017
Ailiet, Luc, Berquin, Anne, Depreitere, Bart, Desomer, Anja, Dewachter, Johan, Dolphens, Mieke, Dumoulin, Christophe, Forget, Patrice, Fraselle, Virginie, Hans, Guy, Hoste, Davy, Jonckheer, Pascale, Mahieu, Geneviève, Michielsen, Jef, Nielens, Henrie, Orban, Thomas, Parlevliet, Thierry, Simons, Emmanuel, Tobbackx, Yannick, Van Wambeke, Peter, Van Zundert, Jan, Vanderstraeten, Jacques, Vanschaeybroeck, Patrick, Vlaeyen, Johan   +23 more
core   +1 more source

Immediate relief of herniated lumbar disc-related sciatica by ankle acupuncture

, 2017
Anfeng Xiang, Mingshu Xu, Yan Liang, Jinzi Wei, Sheng Liu   +4 more
openalex   +1 more source

Comment on Williams NH, et al.: a systematic review and meta-analysis of biological treatments targeting tumour necrosis factor α for sciatica (Eur Spine J, 2013;22(9):1921–35) [PDF]

, 2014
Jing Wang, Guitao Li, Hongtao Sun
openalex   +1 more source

Bipedalism or bipedalisms: The os coxae of StW 573

Journal of Anatomy, EarlyView.
There has been a long debate about the possibility of multiple contemporaneous species of Australopithecus in both eastern and southern Africa, potentially exhibiting different forms of bipedal locomotion. Here, we describe the previously unreported morphology of the os coxae in the 3.67 Ma Australopithecus prometheus StW 573 from Sterkfontein Member 2
Robin Crompton, Sarah Elton, Jason Heaton, Travis Pickering, Kristian Carlson, Tea Jashashvili, Amelie Beaudet, Laurent Bruxelles, Kathleen Kuman, Susannah K. Thorpe, Eishi Hirasaki, Christopher Scott, William Sellers, Todd Pataky, Ronald Clarke, Juliet McClymont   +15 more
wiley   +1 more source

Unraveling proteomic signatures and neuroinflammatory networks in a CCI rat model of early sciatica: insights for neuropathic pain mechanisms. [PDF]

Front Mol Neurosci
Li X, Wang X, Song J, Jiang B, Wen Y, Wang Y, Liu B, Zheng X.   +7 more
europepmc   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Druggable Genome-Wide Mendelian Randomization Identifies Distinct Therapeutic Targets for Low Back Pain, Intervertebral Disk Degeneration, and Sciatica. [PDF]

J Pain Res
Sun A, Li Z, Du Y, Liu H, Zhan Q, Liu Z.
europepmc   +1 more source