Results 81 to 90 of about 24,008 (242)

The clinical and cost-effectiveness of stratified care for patients with sciatica: the SCOPiC randomised controlled trial protocol (ISRCTN75449581)

BMC Musculoskeletal Disorders, 2017
Background Sciatica has a substantial impact on patients, and is associated with high healthcare and societal costs. Although there is variation in the clinical management of sciatica, the current model of care usually involves an initial period of ‘wait
Nadine E. Foster, Kika Konstantinou, Martyn Lewis, Reuben Ogollah, Kate M. Dunn, Danielle van der Windt, Ruth Beardmore, Majid Artus, Bernadette Bartlam, Jonathan C. Hill, Sue Jowett, Jesse Kigozi, Christian Mallen, Benjamin Saunders, Elaine M. Hay   +14 more
doaj   +1 more source

Harnessing Piezoelectric Biomaterials for Pathogenic Eradication and Tissue Regeneration

Exploration, EarlyView.
This review highlights recent advances in piezoelectric biomaterials for antibacterial therapy and tissue regeneration, discussing material classifications, catalytic mechanisms, property enhancements, biomedical applications, and future challenges in clinical translation.
Wenxuan Mao, Xiaoye Li, Ao He, Meng Ding, Yu Zhang, Zhuo Dai, Qiang Li, Weijun Xiu, Yanling Hu, Yongbin Mou, Dongliang Yang, Heng Dong   +11 more
wiley   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

Ibrain, EarlyView.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma, Yingqi Ma, Claudia Marino, Alessandro Poma   +3 more
wiley   +1 more source

Causal association between circulating inflammatory markers and sciatica development: a Mendelian randomization study

Frontiers in Neurology
BackgroundThis research explores the causal association between circulating inflammatory markers and the development of sciatica, a common and debilitating condition.
Yang Wu, Yi Lin, Mengpei Zhang, Ke He, Guihua Tian   +4 more
doaj   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

Ibrain, EarlyView.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard, Vivian Kapio Abem, Sagor Kumar Roy   +2 more
wiley   +1 more source

Construction and Validation of a Preoperative Surgical Difficulty Prediction and Risk Stratification System for Posterior Spinal Deformity Correction Surgery Based on Machine Learning ‐ Multicenter Cohort Study

iMetaMed, EarlyView.
A web calculator, trained on multicenter data with seven Boruta‐selected preoperative features, predicts prolonged operative time for posterior spinal deformity correction to enable individualized planning and optimized operating‐room resources. ABSTRACT Operative duration reflects surgical complexity and is valuable for perioperative planning.
Chan Xu, Jialiang Zheng, Chengliang Yin, Runmin Li, Xubin Quan, Binghao Chen, Zhaohui Hu, Tongqing Luo, Hao Jiang, Xuewen Hou, Qizhong Xu, Weiheng He, Liang Chen, Anfa Chen, Xin Zhou, Wei Huang, Sen Gao, Jiali Yu, Zhi‐Ri Tang, Yusi Zhang, Kai Wang, Shi‐Nan Wu, Wencai Liu, Xiangdong Xi, Haizhen Ding, Qiang Liu, Haopeng Luan, Wenle Li   +27 more
wiley   +1 more source

Nanoparticle‐integrated electrostimulation‐responsive biomaterials: Innovations in drug delivery and tissue repair in clinical regenerative medicine

Interdisciplinary Medicine, EarlyView.
Schematic representation of nanoparticle‐integrated electrostimulation‐responsive biomaterials for controlled drug delivery and tissue regeneration. Electroactive scaffolds including conductive polymers, electroresponsive hydrogels, and piezoelectric matrices are shown incorporating therapeutic nanoparticles (such as iron oxide, silver, and carbon ...
Peyman Halvaeikhanekahdani, Sajad Zandi, Qadeer Ahmad, Hadiseh Payravand   +3 more
wiley   +1 more source

Understanding sciatica: illness and treatment beliefs in a lumbar radicular pain population. A qualitative interview study [PDF]

, 2019
R. Goldsmith, Nefyn Williams, Fiona Wood
openalex   +1 more source

3D‐Printed Models in Oral Surgery Simulation Training: A Scoping Review

Journal of Dental Education, EarlyView.
ABSTRACT Background Advancements in three‐dimensional (3D) printing have introduced innovative tools for medical and dental education. In dental surgery, 3D‐printed simulation models offer valuable presurgical training. This review explores the scope, study types, key findings, limitations, and future research needs to enhance their application in ...
Shahrzad Rahimizadeh Nahavandi, Leila Gholami, Amir Parham Pirhadi Rad, Morteza Ghojazadeh, Kevin Aminzadeh, Rana Tarzemany   +5 more
wiley   +1 more source