Results 81 to 90 of about 795,825 (267)
Selection of Liner Materials and Design of Hazardous Water Facilities in Saudi Arabia
Sultan Qaboos University Journal for Science, 2001 Rapid development in Saudi Arabia has produced a broad spectrum of wastes. In the last two decades, several refineries and petrochemical industries have been established.
Sahel N. Abduljauwad, Ali M. Dakkak
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Determination of Ascorbic Acid in Oman Citrus Fruits
Sultan Qaboos University Journal for Science, 2007 Omani citrus fruits were analyzed for their Vitamin C (ascorbic and AA) content by a titration method involving N-bromosuccinimide (NBS) as an oxidizing agent and by high performance liquid chromatography.
KS.M.Z. Al-Kindi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The Seroprevalence of Human Toxoplasmosis in Oman
Sultan Qaboos University Journal for Science, 1996 The prevalence of Toxoplasma 1gG antibodies was studied in three age groups (children. blood donors and pregnant women) in Oman. The highest prevalence rate was shown by pregnant women (39.5%).
M.A. Idris +2 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Applying Halstead's Metric to Oberon Language
Sultan Qaboos University Journal for Science, 1999 Oberon is a small, simple and difficult programming language. The guiding principle of Oberon was a quote from Albert Einstein: "Make it as simple as possible, but not simpler".
Fawaz Ahmed Masoud
doaj +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source