Results 51 to 60 of about 6,304,582 (340)

Electronic evidence and the meaning of "original" [PDF]

open access: yes, 2009
Article based on a paper given at the Tokyo Institute of Technology, Graduate School of Decision Science and Technology, Ookayama-campus, Tokyo.Article by Stephen Mason published in Amicus Curiae - Journal of the Society for Advanced Legal Studies.
Mason, Stephen
core  

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Understanding migrants in COVID-19 counting: Rethinking the data-(in)visibility nexus

open access: yesData & Policy, 2021
The COVID-19 pandemic confronts society with a dilemma between (in)visibility, security, and care. While invisibility might be sought by unregistered and undocumented people, being counted and thus visible during a pandemic is a precondition of existence
Annalisa Pelizza   +2 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Reconstructions: recreating science and technology of the past [PDF]

open access: yes, 2011
Historic reconstructions have become a decisive tool in the history of science and technology.
Staubermann, Klaus
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Science democratised = expertise decommissioned [PDF]

open access: yes, 2007
Science and expertise have been antithetical forms of knowledge in both the ancient and the modern world, but they appear identical in today’s postmodern world, especially in Science & Technology Studies (STS) literature. The ancient Athenians associated
Fuller, Steve
core   +2 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

ST(&)S: Martyn Pickersgill Talks with Sheila Jasanoff

open access: yesEngaging Science, Technology, and Society, 2018
In this interview, Sheila Jasanoff and Martyn Pickersgill discuss the contested meanings of STS, defined as either “science and technology studies” (often associated with European origins) or “science, technology, and society” (commonly seen as ...
MARTYN PICKERSGILL1, SHEILA JASANOFF
doaj   +1 more source

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