Results 61 to 70 of about 6,304,582 (340)

Barriers to Pursuing STEM-Related Careers: Perceptions of Hispanic Girls Enrolled in Advanced High School STEM Courses [PDF]

, 2018
Researchers indicate that the United States has fallen behind other nations in science, technology, engineering, and mathematics (STEM) education (President\u27s Council of Advisors on Science and Technology, 2010, 2012).
Bustamante, Rebecca M., Combs, Julie P., Vijil, Veronica   +2 more
core   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Can Democracy Survive AI?

Sociologica
This essay examines the fundamental tension between artificial intelligence technologies and democratic governance, arguing that AI’s inherent tendencies toward centralization and control pose significant challenges to democratic societies.
Gina Neff
doaj   +1 more source

Etnografando stories: experimentações sociotécnicas nas mídias digitais [PDF]

Horizontes Antropológicos
Resumo Inspirada em discussões dos science and technology studies e sobre etnografia em contextos online, busquei descrever como se dão algumas associações sociotécnicas nas mídias digitais.
Stephanie Ribeiro
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Science, technology, and society studies

, 2016
This entry examines contemporary scholarship on media and information technologies at the intersection of science and technology studies (STS) and communication studies. The term “media and information technologies” is used to bring together a variety of research frameworks that seek to capture symbolic, social, cultural, or political aspects of ...
Siles González, Ignacio, Boczkowski, Pablo Javier, Crooks, Roderic N., Lievrouw, Leah A.   +3 more
openaire   +3 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Sensing Landscape as a Media Object

Diseña, 2020
Array-based remote sensing has been influencing knowledge practices across many fields, from geology, military planning, and archaeology to landscape architecture and artistic research.
Saadia Mirza
doaj   +1 more source