Results 131 to 140 of about 14,333,906 (401)

Science with a difference : organising planet walk in Malta [PDF]

open access: yes, 2005
Even to this very day, many look at science as something that is done in a classroom. Perhaps, an experiment conducted in a laboratory may relate well to what one understands by ‘Science’.
2nd International Conference Hands-on Science : Science in a Changing Education   +1 more
core  

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Accepting the Challenges: The Emerging Role of Grand Rapids Community College in Preparation of New Teachers [PDF]

open access: yes, 1998
In 1992, Grand Rapids Community College (GRCC) was one of six community colleges invited to participate in a NSF initiative to improve science and mathematics teaching within the state of Michigan.
Hesse, J.
core   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Cosmology and Science Education: Problems and Promises

open access: yes, 2012
Cosmology differs in some respects significantly from other sciences, primarily because of its intimate association with issues of a conceptual and philosophical nature.
Kragh, Helge
core  

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