Results 141 to 150 of about 16,457,912 (317)
Journal of Methodology of Social Sciences and Humanities; No. 116
The main objective of Methodology of Humanities and Social Sciences (MSSH) is to provide an intellectual platform for national and international researchers to discuss their most recent findings related to philosophical foundations and methodology of ...
Methodology of Social Sciences and Humanities, J (via Mendeley Data)
core +1 more source
Institute of Agricultural and Environmental Sciences [PDF]
, 2010 Full textWe care about Nature. We seek to promote a caring and sustainable approach to human activity in Nature. Our role is to recognize that cultural and natural values are often interrelated and they should be considered in an integrated ...
Vollmer, Elis (compiler) +1 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Journal of Islam and Social Sciences; No. 30
Today, the importance of the fundamental role of the social sciences in the realization of a coherent and civilizing intellectual system and their application to social control and development in Islamic societies is not overlooked. In addition, research
Islam and Social Sciences, J (via Mendeley Data)
core +1 more source
Le Monde d'aujourd'hui. Les sciences sociales au temps du Covid
, 2020 Dès le déclenchement de ce « fait social total » que fut la pandémie de Covid-19, la communauté scientifique de Sciences Po s'est lancée dans des analyses collectives et interdisciplinaires pour tenter de comprendre sa signification. Sidérant, impensable,
Ragot, Xavier +2 more
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Journal of Islam and Social Sciences; No. 16
The main objective of the Journal of Islam and Social Sciences is to provide an intellectual platform for national and international researchers to discuss their most recent findings related to the relationship of Islam and social sciences in Iran.
Islam and Social Sciences, J (via Mendeley Data)
core +1 more source