Results 61 to 70 of about 11,994,000 (257)

Annual report on evaluation findings 2001 [PDF]

, 2001
French version available in IDRC Digital Library: Rapport annuel sur les constatations des évaluations 2001Section I presents findings from the IDRC Evaluation Unit (2000-2001) drawn from 15 evaluations with specific attention to three areas of program ...
IDRC. Evaluation Unit
core  

An Evaluation of World Bank Group Assistance, Overview Report

, 2004
(covering the activities of IBRD/IDA), the Operations Evaluation Group (covering IFC), and the Operations Evaluation Unit (covering MIGA). The purpose of the evaluation is to assess the effectiveness of the World Bank Group (WBG) in helping its member ...
Operations Evaluation Department
core   +1 more source

Certification of the industry reference standard for the specific activity of «BiVac polio» - live attenuated bivalent oral polio vaccine type 1 and 3

Биопрепараты: Профилактика, диагностика, лечение, 2018
The standardization and control of «BiVac polio» (live attenuated bivalent oral polio vaccine type 1 and 3) developed by M. P. Chumakov Institute of Poliomyelitis and Viral Encephalitides of the Russian Academy of Medical Sciences, called for ...
E. V. Karpova, A. D. Sangadzhieva, T. V. Mamontova, O. V. Fadeykina, R. A. Volkova, K. A. Sarkisyan, A. A. Movsesyants   +6 more
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

CGIAR Standards for Independent External Evaluation [PDF]

, 2023
The Standards provide the details, modalities and common operating frameworks for implementation of the Evaluation Policy in the CGIAR.
CGIAR Independent Evaluation Arrangement
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Interchangeability of glibenclamide-containing drugs

Регуляторные исследования и экспертиза лекарственных средств, 2018
The article analyses the problem of interchangeability of glibenclamide-containing drugs that sometimes lack therapeutic equivalence even though their bioequivalence has been proven.
G. I. Gorodetskaya, E. V. Shikh, M. V. Zhuravleva, S. Yu. Serebrova, E. A. Sokova, O. V. Muslimova, T. V. Aleksandrova, I. A. Mazerkina, S. G. Rudnev   +8 more
doaj  

Russian and International Regulatory Recommendations for the Development and Marketing Authorisation of COVID-19 Vaccines in the Context of the Pandemic

Биопрепараты: Профилактика, диагностика, лечение, 2020
The progress of the COVID-19 pandemic initiated research to develop vaccines against this novel coronavirus infection. The WHO and national regulatory authorities in many countries have elaborated guidelines to speed up the development and authorisation ...
A. A. Soldatov, Zh. I. Avdeeva, V. P. Bondarev, V. A. Merkulov, V. D. Mosyagin, V. B. Ivanov, D. V. Gorenkov, L. M. Khantimirova   +7 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Working together to strengthen skills : IDRC's strategic evaluation of capacity development, phase 3; developing the framework [PDF]

, 2007
French version available in IDRC Digital Library: Renforcement concerté des capacités : phase 3 de l'évaluation stratégique des activités de renforcement des capacités du CRDI; élaboration du cadre d'évaluationThis “Evaluation Highlights” newsletter ...
IDRC. Evaluation Unit
core