Results 101 to 110 of about 44,866 (295)

Views from drone filming construction progress of Science Gateway site

open access: yes, 2022
The CERN Science Gateway building will be a new visitor and education centre. Its aim is to engage the public in science and promote scientific education among them.
Brice, Maximilien
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Editorial bullying: an exploration of acts impacting publication ethics and related environment

open access: yesFrontiers in Research Metrics and Analytics
Bullying and misconduct in the realm of scientific and scholarly publishing have the potential to jeopardize the transparency and integrity of academic discourse.
Fawad Javed   +2 more
doaj   +1 more source

Getting Past the Gateway: An Exploratory Case on Using Utilitarian Scientific Literacy to Support First-Year Students At-Risk of Leaving STEM

open access: yesEducation Sciences, 2019
First-year students who enter college pursuing a STEM degree still face challenges persisting through the STEM pipeline (Chen, 2013; Leu, 2017). In this case study, researchers examine the impact of a utilitarian scientific literacy based academic ...
Brittany Chambers   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

E-cigarettes: The holy grail of smoking cessation or a new addiction?

open access: yesUniversity of Ottawa Journal of Medicine, 2014
Since its introduction, e-cigarettes have evoked strongly opposed views and much passion from both proponents and opponents. The proponents of e-cigarettes view the product as an effective smoking cessation tool and a potential savior for millions of ...
Alexander Dufort, Aida Owila
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

DeepForge: A Machine Learning Gateway for Scientific Workflow Design

open access: yes, 2018
DeepForge is an open source platform for deep learning designed for promoting reproducibility, simplicity and rapid development within diverse scientific domains.
Volgyesi, Peter   +3 more
openaire   +1 more source

The Role of the TPA-70 Gateway-Network in Promoting Transborder Data Flow of Scientific Information in an International Setting [PDF]

open access: yes, 1981
This paper describes the recently developed "TPA-70 gateway-network" of the International Institute for Applied Systems Analysis (IIASA) in Austria, and of the Institute for Computerization and Automation of the Hungarian Academy of Sciences (SZTAKI) in ...
Labadi, A., Sebestyen, I.
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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