Results 11 to 20 of about 606,604 (206)

Interference in science: scientists’ perspectives on their ability to communicate and conduct environmental research in Canada

FACETS, 2023
When researchers are sufficiently resourced to conduct research and communicate their findings, the knowledge produced can benefit the environment and society through policy.
Manjulika E. Robertson, Samantha M. Chu, Anika Cloutier, Philippe Mongeon, Don A. Driscoll, Tej Heer, Alana R. Westwood   +6 more
doaj   +1 more source

A survey of early-career researchers in Australia

eLife, 2021
Early-career researchers (ECRs) make up a large portion of the academic workforce and their experiences often reflect the wider culture of the research system.
Katherine Christian, Carolyn Johnstone, Jo-ann Larkins, Wendy Wright, Michael R Doran   +4 more
doaj   +1 more source

Fine Particulate Matter and Total Mortality in Cancer Prevention Study Cohort Reanalysis

Dose-Response, 2017
Background: In 1997 the US Environmental Protection Agency (EPA) established the National Ambient Air Quality Standard (NAAQS) for fine particulate matter (PM 2.5 ), largely because of its positive relationship to total mortality in the 1982 American ...
James E. Enstrom
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Andean Fabaceae Species with Pharmacological Potential: Exploration of Antioxidant, Anticarcinogenic, and Antimicrobial Properties

Agriculture
The objective of the present study was to explore the pharmacological potential of three Andean Fabaceae species—Prosopis pallida (algarrobo), Caesalpinia spinosa (tara), and Inga feuilleei (pacae)—as well as their phytochemical composition and ...
Jhoseline Stayce Guillén-Sánchez, Walter Rojas-Villacorta, Ricardo Diego Duarte Galhardo de Albuquerque   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

SCIENCE AND HOMOSEXUALITY: POLITICAL BIAS IN MODERN ACADEMIA

Russian Journal of Education and Psychology, 2019
Allegations like “proven genetic reason for homosexuality” or “proven inefficacy of sexual orientation change efforts” are put forward at popular science educational events for scientifically unsophisticated people.
Viktor Grigorievitsch Lysov
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Health research protocols: a template for empirical bioethics and other investigations

Health Research Policy and Systems
We have formalized a protocol template suitable for all types of humanities and social sciences investigations in the domain of health, including empirical bioethics in particular.
Henri-Corto Stoeklé, Christian Hervé
doaj   +1 more source