Results 71 to 80 of about 1,497,668 (296)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The linkage between global financial crises, corporate social responsibility and climate change: unearthing research opportunities through bibliometric reviews

Frontiers in Climate
Financial matters, corporate social responsibility (CSR), climate change, and other sustainable solutions all work in tandem. In order to provide a thorough understanding of the integration between various components during crises, it is necessary to ...
Abdella K. Chebo, Abdella K. Chebo, Shepherd Dhliwayo, Muhdin M. Batu, Muhdin M. Batu   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Scientometric analysis of scientific outputs in the field of digital marketing [PDF]

مجله علم‌سنجی کاسپین
Background and aim: The internet has provided marketers with a new path for greater creativity, resulting in increased transparency in marketing. The expansion of digital media platforms and the commercial use of the internet have transformed the ...
Ismael Mostafavi, Yeganeh Dastar
doaj  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Drawing a scientific map of the drivers of agricultural land use change with a scientometric approach [PDF]

مجله علم‌سنجی کاسپین
Background and aim: This study was conducted to analyze the scientometrics of agricultural land use changes between 2000 and 2024 and aims to identify the main drivers of these changes.
Freshteh Avatefi Akmal, Yaser Mohammadi
doaj  

Cassava (Manihot esculenta Crantz): Evolution and Perspectives in Genetic Studies

Agronomy
Cassava (Manihot esculenta Crantz) is essential for global food security, especially in tropical regions. As an important genetic resource, its genetics plays a key role in crop breeding, enabling the development of more productive and pest- and disease ...
Vinicius Campos Silva, Gustavo Reis de Brito, Wellington Ferreira do Nascimento, Eduardo Alano Vieira, Felipe Machado Navaes, Marcos Vinícius Bohrer Monteiro Siqueira   +5 more
doaj   +1 more source

Co-citation Analysis: An Overview [PDF]

, 2011
This article gives an overview of co-citation analysis and its applications in tracking the linkages among the intellectual works and mapping the evolutionary structure of scientific disciplines.
Bhanumurthy, K., Kademani, B. S., Sagar, Anil, Surwase, G.   +3 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source