Results 61 to 70 of about 4,444,969 (268)

Unilateral stimulation of the lateral division of the dorsal telencephalon induces synaptic plasticity in the bilateral medial division of zebrafish

Scientific Reports, 2017
This study was aimed to evaluate the synaptic plasticity in projections from the dorsal lateral region (Dl) to the bilateral dorsal medial region (Dm) of the zebrafish telencephalon.
Yao-Ju Wu, Yu-Lan Chen, Tso-Hao Tang, Ming-Chong Ng, Tamara G. Amstislavskaya, Maria A. Tikhonova, Yi-Ling Yang, Kwok-Tung Lu   +7 more
doaj   +1 more source

Fractal lacunarity of trabecular bone in vertebral MRI to predict osteoporotic fracture risk in over-fifties women. The LOTO study

BMC Musculoskeletal Disorders, 2021
Background Osteoporotic fractures are a major cause of morbidity in the elderly. Menopausal women represent the population with the highest risk of early osteoporosis onset, often accompanied by vertebral fractures (VF).
Annamaria Zaia, Roberto Rossi, Roberta Galeazzi, Manuela Sallei, Pierluigi Maponi, Pietro Scendoni   +5 more
doaj   +1 more source

Soft peer review: social software and distributed scientific evaluation [PDF]

, 2008
The debate on the prospects of peer-review in the Internet age and the increasing criticism leveled against the dominant role of impact factor indicators are calling for new measurable criteria to assess scientific quality. Usage-based metrics offer a
Taraborelli, D.
core  

Empirical-Scientific Model of Geography [PDF]

QUAGEO, 2011
Empirical-Scientific Model of Geography The article presents a philosophical-methodological conception of an empirical-scientific model of geography as an empirical science. It consists of an introduction and two parts. The introduction discusses the notion of philosophical-methodological models of geography and philosophical ...
openaire   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Fen ve Matematik Öğretmen Adaylarının Modellerin Bilim ve Fendeki Rolüne ve Amacına İlişkin Algıları

Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2009
Bilimsel süreçlerin ve bilimsel okuryazarlığın ayrılmaz birer parçasıolan modeller, betimledikleri sistemin basitleştirilmiştemsilleridir ve nesneleri, olayları, fikirleri ya da soyut kavramlarıalgılanır kılan araçlardır.
Nilüfer Cerit Berber, Hatice Güzel
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Applying models of scientific terms' surroundings in classification of scientific publications

Lietuvos Matematikos Rinkinys, 2004
This paper considers a problem of classification of scientific publications wich is treated here as a problem of finding keywords. Keywords are determined by making use of statistical analysis of distribution of scientific terms.
Vaidas Balys, Rimantas Rudzkis
doaj   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source