Results 121 to 130 of about 662,628 (289)
Ekonomika Nauki, 2015 The article presents an economic analysis of expenses for patenting and by using leading technical universities as an example, it demonstrates the lack of economic practicability of patent activity in a situation, when only 6–12% of patents for ...
V. G. Zinov, O. I. Kupriyanova
doaj
Chromatographic-Based Platforms as New Avenues for Scientific Progress and Sustainability. [PDF]
Molecules, 2022 Câmara JS +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Scientific Progress During Peacetime: Current Epistemological Trends [PDF]
This analytical study explores the nature of scientific progress connected to current philosophical definitions and the role of institutional governance in promoting this progress.
Parker, D. A.
core +3 more sources
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
The scientific progress and prospects of artificial intelligence in digestive endoscopy: A comprehensive bibliometric analysis. [PDF]
Medicine (Baltimore), 2022 Gan PL +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Declaration of common standards for the preregistration of animal research-speeding up the scientific progress. [PDF]
PNAS Nexus, 2022 Heinl C +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source