Results 111 to 120 of about 1,214,788 (299)
No abstract available.
Pierre J.T. de Villiers
doaj +1 more source
Scientific publishing needs disruption [PDF]
Steve Jobs, visionary and co-founder of Apple Inc, and famed for his competitive streak, commented at the launch of the Kindle, Amazon's new electronic book reader, that ‘it doesn't matter how good or bad the product is; the fact is that people don't read anymore’.[1][1] Scientific ...
openaire +2 more sources
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Publishing activity of Komi Scientific Center of the Ural Branch of the Russian Academy of Sciences
The history of the publishing activity of the large scientific subdivision of the Russian Academy of Sciences is presented for the first time. The editorial-publishing department of Komi Scientific Centre is a leader of the scientific book publishing in ...
L. P. Roshchevskaya
doaj
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Centre Mersenne : diamond open access scientific publishing infrastructure [PDF]
International audienceThe Centre Mersenne for Open Scientific Publishing is a not-for-profit, academic-led, full-featured publishing infrastructure for Diamond open access scientific publications prepared in LaTeX.Launched in January 2018 by researchers ...
Serlet, Murielle, Vaudaine, Célia
core

