Results 121 to 130 of about 1,160,518 (299)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Bioline Publications : How its evolution has mirrored the growth of the Internet [PDF]

open access: yes, 2001
Bioline was set up in 1993 as a result of an increasingly loud rumble of dissatisfaction among scientists about the way research information was (or was not) distributed.
Kirsop, Barbara   +2 more
core  

Reassembling scholarly publishing: Institutional repositories, open access, and the process of change

open access: yes, 2007
The domain of scholarly publishing is undergoing rapid change. Change has been instigated and produced by the Internet and open access systems – such as disciplinary and institutional repositories and open access journals.
Cecez-Kecmanovic, Dubravka   +1 more
core   +1 more source

Scientific Data at MBSJ 2014

open access: yes, 2014
Yoko Shintani from Nature Publishing Group discusses reproducibility and the role of data journals in scientific research.
Scientific Data (663274)
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

History and development prospects of the regional encyclopedia publishing in Russia

open access: yesЕнциклопедичний Вісник України, 2015
Anastasiya Korochkina
doaj   +1 more source

„Beyond Access: New Ideas to Survive APC, AI, Predatory Publishing and a Changing World“ – eine Nachbesprechung mit ChatGPT

open access: yesGMS Medizin – Bibliothek – Information
This satirical article is based on a presentation given at the 2024 AGMB Annual Conference in Mainz and humorously explores the usage of AI in scientific publishing.
Vogel, Christian
doaj   +1 more source

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