Results 111 to 120 of about 253,424 (250)
Scientific Antirealists Have Set Fire to Their Own Houses [PDF]
, 2017 Scientific antirealists run the argument from underconsideration against scientific realism. I argue that the argument from underconsideration backfires on antirealists’ positive philosophical theories, such as the contextual theory of explanation (van ...
Park, Seungbae
core +2 more sources
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Sr. Realista estructural, tenemos un problema: la carga ontológica de las matemáticas
Principia: An International Journal of Epistemology, 2010 The aim of this note is to undermine structural realism by testing the soundness of its main claim. If scientific theories represent the structure of the world, structural realism needs a general account of representation.
Carlos M. Madrid Casado
doaj
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Em Prol do Realismo Científico no Ensino
Ciência & EducaçãoResumo: Diante de exemplos atuais de atitudes anticientíficas com resultados perniciosos à saúde pública, buscamos problematizar o ensino de ciências em moldes sociologistas que, embora enfatizem aspectos relevantes da atividade científica, são limitados
Luiz Henrique Martins Arthury +1 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Evolution of the Criteria of "Brain Death": A Critical Analysis Based on Scientific Realism and Christian Anthropology. [PDF]
Linacre Q, 2019 Nguyen D.
europepmc +1 more source
The Problem of Realism in Theoretical and Critical Reception of I. Franko [PDF]
, 2012 У статті доведено, що реалізм в осмисленні І. Франка становив парадигму, яка розгорталася від «науко¬вого реалізму» до «ідеального». Концепція «наукового реалізму» синтезувала теорію класичного реалізму ХІХ ст.
Goloviy, O. М., Головій, О. М.
core