Results 91 to 100 of about 5,759,774 (291)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Group Structural Realism [PDF]
, 2009 We present a precise form of structural realism, called 'group structural realism,' which identifies 'structure' in quantum theory with symmetry groups.
Roberts, Bryan W., Bryan W. Roberts
core +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
How not to be a Realist or why we Ought to Make it Safe for Closet Structural Realists to Come out. [PDF]
, 2010 When it comes to name-calling, structural realists have heard pretty much all of it. Among the many insults, they have been called ‘empiricist anti-realists’ but also ‘traditional scientific realists’.
Votsis, Ioannis
core
The realist claim of fallibilism: A critique of the realism of Karl Popper
Pensamiento. Revista de Investigación e Información Filosófica, 2015 This article revises Karl Popper’s realism and examines how far he was a realist or simply he tried to be. Distinguishing between two areas of realism, a general one against the idealism, and the other more specific as part of the philosophy of the ...
Rafael Fayos Febrer
doaj
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Realism and objectivism in quantum mechanics [PDF]
, 2012 The present study attempts to provide a consistent and coherent account of what the world could be like, given the conceptual framework and results of contemporary quantum theory. It is suggested that standard quantum mechanics can, and indeed should, be
Karakostas, V., Karakostas, Vassilios
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
American Legal Realism: Research Programme and Policy Impact
Utrecht Law Review, 2017 The article addresses two questions:1. Can Legal Realism be seen as a scientific research programme enabling growth of knowledge? To answer that question, the author uses Lakatos’s work on the methodology of scientific research programmes as a frame of ...
Frans L. Leeuw
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source