Results 101 to 110 of about 5,759,774 (291)

Realismo Científico Empirista?

open access: yesPrincipia: An International Journal of Epistemology, 1997
In his influential criticism of scientific realism, Bas van Fraassen assumes that this doctrine is incompatible with empiricism, according to which the sole ultimate basis of knowledge is experience.
Sílvio Seno Chibeni
doaj  

Em Prol do Realismo Científico no Ensino

open access: yesCiência & Educação
Resumo: Diante de exemplos atuais de atitudes anticientíficas com resultados perniciosos à saúde pública, buscamos problematizar o ensino de ciências em moldes sociologistas que, embora enfatizem aspectos relevantes da atividade científica, são limitados
Luiz Henrique Martins Arthury   +1 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Semantic Incommensurability and Scientific Realism [PDF]

open access: yes, 2007
This paper reviews the situation with respect to the referential approach to the problem of semantic incommensurability. It argues that the thesis of semantic incommensurability does not pose a significant threat to scientific realism.
Sankey, Howard
core  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Thinking About the Ultimate Argument for Realism [PDF]

open access: yes, 2003
The aim of this paper is to rebut two major criticisms of the No-Miracles Argument for Realism. The first comes from Musgrave (1988). The second comes from Colin Howson (2000).
Psillos, Stathis
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Experimental Realism Defended: How Inference to the Most Likely Cause Might Be Sound [PDF]

open access: yes, 2005
On a purely epistemic understanding of experimental realism, manipulation affords a particularly robust kind of causal warrant, which is – like any other warrant – defeasible.
Suárez, Mauricio, Mauricio Suárez
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy