Results 101 to 110 of about 253,424 (250)
Robust Realism for the LIfe Sciences [PDF]
Although scientific realism is the default position in the life sciences, philosophical accounts of realism are geared towards physics and run into trouble when applied to fields such as biology or neuroscience.
Eronen, Markus
core +1 more source
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Critical Realism and Statistical Methods: A Response to Nash [PDF]
This article offers a defence of critical realism in the face of objections Nash (2005) makes to it in a recent edition of this journal. It is argued that critical and scientific realisms are closely related and that both are opposed to statistical ...
Bhaskar R. +13 more
core +3 more sources
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
The realist claim of fallibilism: A critique of the realism of Karl Popper
This article revises Karl Popper’s realism and examines how far he was a realist or simply he tried to be. Distinguishing between two areas of realism, a general one against the idealism, and the other more specific as part of the philosophy of the ...
Rafael Fayos Febrer
doaj
American Legal Realism: Research Programme and Policy Impact
The article addresses two questions:1. Can Legal Realism be seen as a scientific research programme enabling growth of knowledge? To answer that question, the author uses Lakatos’s work on the methodology of scientific research programmes as a frame of ...
Frans L. Leeuw
doaj +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Can the empirical sciences contribute to the moral realism/anti-realism debate? [PDF]
An increasing number of moral realists and anti-realists have recently attempted to support their views by appeal to science. Arguments of this kind are typically criticized on the object-level.
Pölzler, Thomas
core
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Realismo Científico Empirista?
In his influential criticism of scientific realism, Bas van Fraassen assumes that this doctrine is incompatible with empiricism, according to which the sole ultimate basis of knowledge is experience.
Sílvio Seno Chibeni
doaj

