Results 71 to 80 of about 240,709 (344)
Realizm i idealizm: struktura problemu (Realism and Idealism: the Structure of the Debate) [PDF]
Analiza i Egzystencja, 2009 The aim of the article is to systematize fundamental concepts involved in the philosophical debate on realism and idealism. In the first (historical) part distinction between appearance and reality (which has its roots in ancient philosophy) is presented
Stanisław Judycki
doaj
Pragmatist Perspectives on Theological and Religious Realism [PDF]
, 2014 This essay first applies the general issue of realism vs. antirealism to theology and the philosophy of religion, distinguishing between several different ”levels’ of the realism dispute in this context.
Pihlström, Sami
core +1 more source
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Scientific Realism without Rigid Designation in Kant's Analogies [PDF]
, 2016 In Kant, Science, and Human Nature, Robert Hanna argues against a version of scientific realism founded on the Kripke/Putnam theory of reference, and defends a Kant-inspired manifest realism in its place. I reject Kriple/Putnam for different reasons than
Landy, David
core
Rescuing religious non-realism from Cupitt [PDF]
, 2006 Don Cupitt's version of religious non-realism based as it is on linguistic constructivism, radical relativism and the view that culture forms human nature has been attacked with devastating effect by realists in the last few years.
Walker, Ruth
core +1 more source
Molecular Oncology, EarlyView.This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci +6 more
wiley +1 more source
Astroparticle physics, a constructive empiricist account
Science & Philosophy, 2019 Astroparticle physics is an interdisciplinary field embracing astronomy, astrophysics and particle physics. In a recent paper on this topic (2012), Brigitte Falkenburg defended that only scientific realism can make sense of it and that realist beliefs ...
Alessio Gava
doaj +1 more source
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source