Results 81 to 90 of about 240,709 (344)
Machine Learning and the Future of Realism [PDF]
, 2017 The preceding three decades have seen the emergence, rise, and proliferation of machine learning (ML). From half-recognised beginnings in perceptrons, neural nets, and decision trees, algorithms that extract correlations (that is, patterns) from a set of
Hooker, Cliff, Hooker, Giles
core +2 more sources
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Belief‐Ful Realism and Scientific Realism
Zygon: Journal of Religion and Science, 2001 Despite tensions between Tillich's category of belief‐ful realism and a view of science that embraces metaphysical and epistemological realism, a constructive relationship can be developed between the two. Both are based on common understandings about reality. Belief‐ful or theonomous realism thus affirms scientific realism.
openaire +2 more sources
Scientific Realism without the Wave-Function: An Example of Naturalized Quantum Metaphysics [PDF]
, 2019 Scientific realism is the view that our best scientific theories can be regarded as (approximately) true. This is connected with the view that science, physics in particular, and metaphysics could (and should) inform one another: on the one hand, science
Allori, Valia
core +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Scientific Realism and Primordial Cosmology [PDF]
, 2016 We discuss scientific realism from the perspective of modern cosmology, especially primordial cosmology: i.e. the cosmological investigation of the very early universe.
Azhar, Feraz, Butterfield, Jeremy
core +1 more source
Critical Realism and Statistical Methods: A Response to Nash [PDF]
, 2007 This article offers a defence of critical realism in the face of objections Nash (2005) makes to it in a recent edition of this journal. It is argued that critical and scientific realisms are closely related and that both are opposed to statistical ...
Bhaskar R. +13 more
core +3 more sources
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
The epistemology of international politics: offensive realism and the Neorealist Scientific Research Program [PDF]
, 2022 Flávio Pedroso Mendes
openalex +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source