Results 111 to 120 of about 6,123,967 (287)

Disconfirmation is not modus tollens

open access: yesThe Reasoner
Scientific disconfirmation has often been thought to be reasoning by modus tollens. This interpretation, however, misconstrues the conditionals in this scientific reasoning in terms of the material conditional, rather than in terms of causal ...
Kenneth Aizawa
doaj   +1 more source

Analogical Reasoning and Working Memory [PDF]

open access: yes, 2012
Analogical Reasoning (AR) is the ability to find a relationship between two objects that is not based on featural (attribute-based) similarities. As such, reasoning by analogy is thought to be crucial in learning and scientific discovery. Analogies
ROBSON, ADAM,JAGO
core  

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

open access: yesFEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

The effect of gizmos virtual laboratory on scientific reasoning in biology education

open access: yesBiosfer
Scientific reasoning skills are fundamental in biology education, yet their development remains a challenge in conventional learning. Virtual laboratories like Gizmos offer a promising alternative to address this issue.
Nadiyyatul Husna   +2 more
doaj   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Teaching Stereochemistry with Multimedia and Hands-On Models: The Relationship between Students' Scientific Reasoning Skills and The Effectiveness of Model Type

open access: yesCenter for Educational Policy Studies Journal
This paper presents an analysis of the use of multimedia and hands-on models on university students’ understanding of stereochemistry. The relationship between students’ scientific reasoning skills and their understanding of stereochemistry was also ...
Rooserina Kusumaningdyah   +5 more
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

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