Results 91 to 100 of about 855,880 (342)
Illegitimate Values, Confirmation Bias, and Mandevillian Cognition in Science [PDF]
, 2021 In the philosophy of science, it is a common proposal that values are illegitimate in science and should be counteracted whenever they drive inquiry to the confirmation of predetermined conclusions.
Peters, Uwe
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Studia PsychologicaThe main aim of our study was to investigate whether COVID-19 conspiracy beliefs are driven by a lack of useful and potentially protective mindware or by contaminated mindware.
Viktória Sunyik, Vladimíra Čavojová
doaj +1 more source
New Water in Old Buckets: Hypothetical and Counterfactual Reasoning in Mach’s Economy of Science [PDF]
, 2019 Ernst Mach’s defense of relativist theories of motion in Die Mechanik involves a well-known criticism of Newton’s theory appealing to absolute space, and of Newton’s “bucket” experiment.
Patton, Lydia
core +2 more sources
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Exploring Students' Scientific Reasoning During Virtual Game in STEAM Problem Solving
LUMATThe purpose of this study was to explore the complexity of scientific reasoning elicited during a virtual STEAM problem-solving activity by challenging questions posed to 53 tenth-grade high school students.
José Julián Kenji López Takegami +3 more
doaj +1 more source
Reactive control and reasoning assistance for scientific laboratory instruments [PDF]
Scientific laboratory instruments that are involved in chemical or physical sample identification frequently require substantial human preparation, attention, and interactive control during their operation.
Levinson, Richard +2 more
core +1 more source
Rationalism, Empiricism, and Evidence-Based Medicine: A Call for a New Galenic Synthesis [PDF]
, 2018 Thirty years after the rise of the evidence-based medicine (EBM) movement, formal training in philosophy remains poorly represented among medical students and their educators.
Webb, William
core +2 more sources
COMPREHENSIVE ANALYSIS OF THE FORT INSTRUMENT: USING DISTRACTOR ANALYSIS TO EXPLORE STUDENTS’ SCIENTIFIC REASONING BASED ON ACADEMIC LEVEL AND GENDER DIFFERENCE [PDF]
, 2021 Minsu Ha +4 more
openalex +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source