Results 71 to 80 of about 855,880 (342)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Dogmatic and social scientific activism in the Lochner era [PDF]
, 2015 The Lochner era has much to say about conceptions of judicial role and judicial activism, and can be used as an analytical example. I examine the era from the aspect of judicial reasoning. The analysis is composed of three main units.
Molnár, András
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Relations between Scientific Reasoning, Culture of Problem Solving and Pupil's School Performance
Journal on Efficiency and Responsibility in Education and Science, 2018 The article reports the results of a study, the main aim of which was to find out correlations among the three components of the Culture of problem solving (reading comprehension, creativity and ability to use the existing knowledge) and six dimensions ...
Eva Hejnová +3 more
doaj +1 more source
CoAKTinG: Collaborative Advanced Knowledge Technologies in the Grid [PDF]
, 2002 Grid infrastructures coupled with semantic web linkage and reasoning open up intriguing new possibilities for scientific collaboration. In this short paper, we outline the research agenda and collaboration technologies under development within the ...
Buckingham Shum, Simon +4 more
core
Influence Of Academic Education Imparted In Basic Sciences On The Scientific Reasoning Skills Of Engineering Students [PDF]
, 2022 Virginia Paredes +6 more
openalex +1 more source
Bayesianism and Scientific Reasoning [PDF]
, 2022 This Element explores the Bayesian approach to the logic and epistemology of scientific reasoning. Section 1 introduces the probability calculus as an appealing generalization of classical logic for uncertain reasoning. Section 2 explores some of the vast terrain of Bayesian epistemology.
openaire +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
A Philosophical Treatise on the Connection of Scientific Reasoning with Fuzzy Logic
Mathematics, 2020 The present article studies the connection of scientific reasoning with fuzzy logic. Induction and deduction are the two main types of human reasoning.
Evangelos Athanassopoulos +1 more
doaj +1 more source
Scaffolding School Pupils’ Scientific Argumentation with Evidence-Based Dialogue Maps [PDF]
, 2008 This chapter reports pilot work investigating the potential of Evidence-based Dialogue Mapping to scaffold young teenagers’ scientific argumentation. Our research objective is to better understand pupils’ usage of dialogue maps created in Compendium to ...
A. Selvin +17 more
core +1 more source