Results 81 to 90 of about 6,123,967 (287)

ASRA: Adaptive Scientific Reasoning Architectures

open access: yes
ASRA (Adaptive Scientific Reasoning Architectures) is a research framework for adaptive reasoning, intervention learning, and hidden action semantics inference in scientific environments.
ilakkuvaselvi manoharan
core   +6 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Health-Related Disinformation: Should We Focus More on Reducing the Mindware Gap or Corrupted Mindware?

open access: yesStudia Psychologica
The main aim of our study was to investigate whether COVID-19 conspiracy beliefs are driven by a lack of useful and potentially protective mindware or by contaminated mindware.
Viktória Sunyik, Vladimíra Čavojová
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

IS SCIENTIFIC REASONING THE KEY TO LEAN SIX SIGMA’S SUCCESS? [PDF]

open access: yesJournal of Defense Resources Management, 2020
The Lean Six Sigma (LSS) process continue to be used throughout the public and private sectors to map processes seeking to make them lean and, thereby, more efficient and effective. We make the argument that the LSS process (i.e.
Mitchell J. MCCARTHY
doaj  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Scientific reasoning ability does not predict scientific views on evolution among religious individuals

open access: yesEvolution: Education and Outreach, 2018
Background Acceptance of evolutionary theory varies widely and is often associated with religious background. Some have suggested there exists an additional relationship between scientific reasoning ability and the acceptance of evolutionary theory.
Katie F. Manwaring   +5 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Exploring Students' Scientific Reasoning During Virtual Game in STEAM Problem Solving

open access: yesLUMAT
The purpose of this study was to explore the complexity of scientific reasoning elicited during a virtual STEAM problem-solving activity by challenging questions posed to 53 tenth-grade high school students.
José Julián Kenji López Takegami   +3 more
doaj   +1 more source

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