Results 61 to 70 of about 855,880 (342)

Latent profile analysis of schizotypy, autistic traits and conspiracy theory beliefs: Associations with cognitive flexibility and scientific reasoning performance

Journal of Experimental Psychopathology, 2022
Schizotypal and autistic traits have both been implicated in the development of conspiracy theory (CT) beliefs. However, there are both similarities and differences between these traits that may increase an individual’s susceptibility to CT beliefs. Past
Neophytos Georgiou, Paul Delfabbro, Ryan Balzan   +2 more
doaj   +1 more source

Eksperimentasi Model Pembelajaran Discovery Learning, Group Investigation, Dan Think Talk Write Dengan Pendekatan Saintifik Terhadap Prestasi Dan Kreativitas Belajar Matematika Pada Materi Bangun Ruang Sisi Datar Ditinjau Dari Kemampuan Penalaran Siswa [PDF]

, 2015
This research aims to know the different effect among learning models used i.e, Discovery Learning (DL) with scientific approach, Group Investigation (GI) with scientific approach, and Think Talk Write (TTW) with scientific approach.
Mardiyana, M. (Mardiyana), Nuraya, N. (Naufalia), Slamet, I. (Isnandar)   +2 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Reasoning under uncertainty: the role of two informal fallacies in an emerging scientific inquiry [PDF]

, 2002
It is now commonplace in fallacy inquiry for many of the traditional informal fallacies to be viewed as reasonable or non-fallacious modes of argument.
Cummings, L
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Assessing College Students’ Quantitative and Scientific Reasoning: The James Madison University Story

Numeracy, 2015
Quantitative and scientific reasoning is a critical student learning outcome in higher education. Data are presented for large samples of undergraduate students who were assessed as entering freshmen and then again after completing 45-70 credit hours ...
John D. Hathcoat, Donna L. Sundre, Mary M. Johnston   +2 more
doaj   +1 more source

On the role of explanatory and systematic power in scientific reasoning [PDF]

, 2015
The paper investigates measures of explanatory power and how to define the inference schema “Inference to the Best Explanation”. It argues that these measures can also be used to quantify the systematic power of a hypothesis and the inference schema ...
Brössel, Peter
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

SCIENTIFIC REASONING ABILITY OF HIGH SCHOOL STUDENTS IN PALANGKA RAYA IN PHYSICS LEARNING

Jurnal Eduscience
Purpose-Scientific reasoning is an essential ability in learning science, including physics. This study aims to assess the scientific reasoning abilities of high school students in Palangka Raya City, focusing on six indicators: conservation reasoning ...
Pri Ariadi Cahya Dinata, Rensi Lukas, Theo Jhoni Hartanto, Desy Kumala Sari   +3 more
doaj   +1 more source