Results 41 to 50 of about 6,123,967 (287)

Bayesianism and Scientific Reasoning [PDF]

open access: yes, 2022
This Element explores the Bayesian approach to the logic and epistemology of scientific reasoning. Section 1 introduces the probability calculus as an appealing generalization of classical logic for uncertain reasoning. Section 2 explores some of the vast terrain of Bayesian epistemology.
openaire   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

IDENTIFIKASI KEMAMPUAN PENALARAN ILMIAH SISWA SMA PADA MATERI SUHU DAN KALOR

open access: yesJurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2017
Scientific reasoning skills help students to explain concepts and argumentations, which is it’s beneficial for student. This article aims to identification pattern of scientific reasoning student that used to solving problems in heat and temperature ...
Ety Rimadani   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Methods of Reasoning in Scientific Discovery [PDF]

open access: yes, 2018
In this paper, we briefly discuss the forms of arguments and the methods of reasoning in scientific experiments, namely, inductive reasoning, abductive reasoning and deductive reasoning.
Nandasena, G.   +2 more
core   +1 more source

Scientific reasoning on paper [PDF]

open access: yesScience, 2018
Education Helping students develop skills in both critical thinking and scientific reasoning is fundamental to science education. However, the relationship between these two constructs remains largely unknown. Dowd et al. examined this issue by investigating how students' critical thinking skills related to scientific reasoning in the context of ...
openaire   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Scientific Reasoning and Implausible Beliefs

open access: yes, 2023
In this project, we aim is to test whether endorsing implausible beliefs is related to scientific reasoning, whether checklists improve people’s scientific reasoning, and whether checklists benefit endorsers more than non-endorsers (more info in ...
Kate Faasse   +4 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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