Results 51 to 60 of about 7,910,103 (275)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Informal fallacies as cognitive heuristics in public health reasoning [PDF]
, 2014 The public must make assessments of a range of health-related issues. However, these assessments require scientific knowledge which is often lacking or ineffectively utilized by the public.
Louise Cummings +2 more
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Scientific Reasoning Is Material Inference: Combining Confirmation, Discovery, and Explanation [PDF]
, 2009 Whereas an inference (deductive as well as inductive) is usually viewed as being valid in virtue of its argument form, the present paper argues that scientific reasoning is material inference, i.e., justified in virtue of its content.
Brigandt, Ingo
core
Influence of training in inquiry-based methods on in-service science teachers’ reasoning skills
Chemistry Teacher International, 2019 Reasoning skills can be described as abilities to use scientific knowledge to identify and solve problems, and to formulate conclusions based on empirical observations.
Bernard Paweł, Dudek-Różycki Karol
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
, 2021 This research examines the effect of the STEM-EFA integrated ADI model for improving students\u27 scientific reasoning skills. The research was conducted in class XI of SMAN 8 Malang with 27 students participating.
Parno, Parno +2 more
core +2 more sources
, 2006 The aim of the study was to evaluate how Hong Kong Occupational Therapy students develop their clinical reasoning abilities and progress through the stages of their undergraduate curriculum.
Dasari, Bhoomiah Dharmiah
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Utamax, 2022 This correlational study on quantitative in nature was conducted to determine the relationship of scientific reasoning skills, critical thinking skills, and performance in Science of senior high school (SHS) students at Tapaz National High School, Capiz,
Leah Mae F. Farillon
doaj +1 more source