Results 201 to 210 of about 22,645,468 (334)

The progeria research foundation 10th international scientific workshop; researching possibilities, ExTENding lives – webinar version scientific summary

, 2021
Leslie B. Gordon, Kelsey Tuminelli, Vicente Andrés, Judith Campisi, Mark W. Kieran, Lynn Doucette, A S Gordon   +6 more
openalex   +2 more sources

Bridging Gaps: Promoting Scientific Research in AOCMF Asia Pacific and Comparison with Latin America. [PDF]

Craniomaxillofac Trauma Reconstr
Menon R, Kanno T, Leung YY, Thelekkat Y, Kulandaswamy GK.   +4 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

The Simple Economics of Basic Scientific Research

Journal of Political Economy, 1959
R. Nelson
semanticscholar   +1 more source

Optimizing clinical scientific research: the cohort intervention random sampling study with historical controls. [PDF]

J Comp Eff Res
de Klerk ND, Berben PB, der Ven MV, Fransen AF, van der Hout-van der Jagt MB, Oei SG, van Laar JO, van den Heuvel ER.   +7 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Statistical primer: how to deal with missing data in scientific research?

Interactive Cardiovascular and Thoracic Surgery, 2018
G. Papageorgiou, S. Grant, J. Takkenberg, M. Mokhles   +3 more
semanticscholar   +1 more source

Exploring Hedging Devices in Scientific Research Papers: A Content Analysis Study of the 'Medical Journal of the Islamic Republic of Iran'. [PDF]

Med J Islam Repub Iran
Hamidi H, Najafi Sarem S, Lotfi AH.
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Exploration of Diversified Talent Training and Collaborative Innovation Models from the Perspective of Scientific Research Team Construction and Collaborative Management Mechanism in Applied Undergraduate Universities

Yuan Gao, Hejian Liu, Yonggang Wang, Li Dong   +3 more
openalex   +2 more sources