Results 101 to 110 of about 7,492,437 (299)
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
VLADIMIR AXIONOV — A CORYPHAEUS OF MOLDOVAN MUSICOLOGY [PDF]
The present article is dedicated to Vladimir Axionov, a remarcable musicologist, researcher, educator, animator of musical life in the Republic of Moldova.
MIRONENCO ELENA
doaj
RipetaScore: Measuring the Quality, Transparency, and Trustworthiness of a Scientific Work. [PDF]
Sumner JQ, Vitale CH, McIntosh LD.
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Performance Reproduction and Prediction of Selected Dynamic Loop Scheduling Experiments
Scientific applications are complex, large, and often exhibit irregular and stochastic behavior. The use of efficient loop scheduling techniques in computationally-intensive applications is crucial for improving their performance on high-performance ...
Ciorba, Florina M. +2 more
core +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Explaining the Black-White Disparity in Preterm Birth: A Consensus Statement From a Multi-Disciplinary Scientific Work Group Convened by the March of Dimes. [PDF]
Braveman P +21 more
europepmc +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Research activities of students as a basic component of future professional activities
Introduction. The competency-based educational paradigm, being the basis for the implementation of the current Federal State Educational Standards of Higher Education, involves focusing on the formation of a competent specialist capable of quickly ...
E. A. Panina
doaj +1 more source
Engeler's scientific work [PDF]
Erwin Engeler was born in Schaffhausen on 13 February 1930 a citizen of Wagenhausen (Thurgovia). He attended school in Diessenhofen (TG) and Schaffhausen and looks back on his various schools warmly as having provided a conducive environment. His schoolwork also left him time for other activities.
openaire +2 more sources

