Results 111 to 120 of about 2,588,444 (261)
In the last pages of our journal, we have reflected "Requirements for writing articles" in Azerbaijani, Russian and English. While some authors take those requirements seriously, others do not authors bring articles to the editorial office or send by e-mail without waiting for the existing rules.
openaire +4 more sources
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
“Scientific Work” is apeer-reviewed international scientific journal that publishes high-quality research in the fields of humanities and social sciences, natural sciences, mathematics and mechanics and technical sciences. The journal was registered by the state in 2007 and has been active since that year.
openaire +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Presenting scientific work-news media theory in presentations, abstracts, and posters. [PDF]
Grech V.
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
The Anatomist James Douglas (1675-1742): His Life and Scientific Work. [PDF]
Koutsouflianiotis KN +4 more
europepmc +1 more source
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Development and Preliminary Validation of a New Measure of Values in Scientific Work. [PDF]
English T +3 more
europepmc +1 more source

