Results 151 to 160 of about 3,068,645 (312)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

UNDERSTANDING THE STRUCTURE OF SCIENTIFIC WORK: BASIC TRAINING IN SCIENTIFIC JOURNAL WRITING TECHNIQUES FOR GRADUATE LEVEL STUDENTS

open access: yesJurnal Layanan Masyarakat (Journal of Public Services)
Basic training in scientific journal writing techniques is an important activity for undergraduate students in understanding the structure of scientific work.
Bambang Suprianto, Suhendra suhendra
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Ambivalent work*s: queer perspectives in art and art history [PDF]

open access: yes
ambivalent work*s presents case studies, close- and against-the-grain readings of art works across different media and geographies, conversations on the epistemological and methodological frameworks of a queerly-informed art history, and artistic ...

core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Scientific Works

open access: yes, 1934
In the last pages of our journal, we have reflected "Requirements for writing articles" in Azerbaijani, Russian and English. While some authors take those requirements seriously, others do not authors bring articles to the editorial office or send by e-mail without waiting for the existing rules.
openaire   +5 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Green groups and grey areas : scientific boundary work, NGOs and environmental knowledge. [PDF]

open access: yes, 2006
In this paper we examine the role of nongovernmental organisations (NGOs) in debates about environmental science and knowledge, using empirical evidence from in-depth interviews with a range of NGOs involved in the waste debate in the United Kingdom.
Donaldson, Andrew   +2 more
core  

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