Results 141 to 150 of about 3,068,645 (312)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Scientific Inquiry in Social Work [PDF]
, 2019 1. Introduction to research2. Beginning a research project3. Reading and evaluating literature4. Conducting a literature review5. Ethics in social work research6. Linking methods with theory7. Design and causality8.
DeCarlo, Matthew
core
Swiss chocolate and free beverages to increase the motivation for scientific work amongst residents: a prospective interventional study in a non-academic teaching hospital in Switzerland. [PDF]
Trials, 2020 Rühle A +8 more
europepmc +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Scientific literacy for sustainability [PDF]
, 2006 We only need to consider public media reports to appreciate that there is growing concern amongst citizens for sustainability. This concern arises from increasing appreciation that the current direction and rate of exploitation of resources is not ...
Murcia, Karen
core +1 more source
Journal of Business Economics and ManagementThis article presents Professor Joanicjusz Nazarko’s outstanding achievements in research, scientific cooperation, teaching and organizational work, in celebration of the 45th jubilee of his scientific work.
Martyna Wilczewska +2 more
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Letters and Scientific Communities [PDF]
We enter the debate about the possibility of collaboration and of rich exchanges among physically distant individuals by offering a literacy perspective on communication to show how the dimensions of writing enable the development of scientific ...
Fayard, Anne-Laure, Metiu, Anca
core +1 more source
CIRCUMSTANCES OF THE FOUNDATION AND ACHIEVEMENTS OF FIRST SCIENTIFIC POSTGRADUATED STUDY IN SOCIAL WORK (2002 TO 2012) [PDF]
, 2013 U radu je prikazan proces uspostavljanja prvog poslijediplomskog znanstvenog studija iz socijalnih djelatnosti. To je poslijediplomski znanstveni studija iz teorije i metodologije socijalnog rada koji je objedinjavao dvogodišnji znanstveni magistarski i ...
Ajduković, Marina +3 more
core +1 more source