Results 61 to 70 of about 2,588,444 (261)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

ACADEMIC PUZZLE - THE RELATIONSHIP BETWEEN ORIGINALITY, PLAGIARISM AND SIMILARITY IN THE CONTENTS OF DOCTORAL THESES [PDF]

open access: yesChallenges of the Knowledge Society
In a world where every individual strives to showcase his originality, peculiarities and traits that make him different from others through all possible means, whether we are talking about the style of clothing, the image on social media, hobbies, the ...
Narcisa-Victoria DĂRĂBAN
doaj  

Factors of formation self-development abilities among university students

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки, 2019
We substantiate the necessity of the student’s self-development ability formation in the conditions of multi-level educational programs implementation in a technical university.
E. A. Molokanova
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

A qualitative study of young workers’ experience of the psychosocial work environment and how this affects their mental health

open access: yesBMC Public Health
Background The evidence base for the relationship between psychosocial work factors and mental health focuses primarily on the general working population but little is known about young workers.
Malte van Veen   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

ІСТОРІЯ ВИКЛАДАННЯ ФІЛОСОФІЇ НА КАФЕДРІ СУСПІЛЬНИХ НАУК ТА УКРАЇНОЗНАВСТВА БУКОВИНСЬКОГО ДЕРЖАВНОГО МЕДИЧНОГО УНІВЕРСИТЕТУ НА ПОЧАТКУ ХХІ СТОЛІТТЯ (2001-2017 рр.)

open access: yesАктуальні питання суспільних наук та історії медицини, 2018
Современный мир диктует новые актуальные принципы развития высшего медицинского и фармацевтического образования. Сейчас четко очерченные приоритеты автономности образовательных учреждений, основой которых является учет идей и пожеланий профессорско ...
Микола СИДОРЕНКО   +1 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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