Results 71 to 80 of about 7,492,437 (299)
Hot Water Dipping in Northern Germany- on farm results after four years of scientific work [PDF]
, 2006 In general, organic grown apples (Malus x domestica Borkh.) are not treated with chemical fungicides to pre-vent storage decay and these fruits may suffer up to 30% decay during storage.
Benduhn, Bastian +4 more
core
Accelerating Scientific Discovery by Formulating Grand Scientific Challenges [PDF]
, 2012 One important question for science and society is how to best promote scientific progress. Inspired by the great success of Hilbert's famous set of problems, the FuturICT project tries to stimulate and focus the efforts of many scientists by formulating ...
D. Helbing +4 more
core +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
THE MEANINGS, PURPOSE AND FUNCTION OF THE CONTEMPORARY RUSSIAN GRADUATE SCHOOL: PROBLEM ANALYSIS
Вестник Северо-Кавказского федерального университета, 2022 The article deals with various aspects of understanding of the modern model of the Russian postgraduate school as a level of higher education. The scientific, normative, statistical materials and data revealing the target and functional basis of ...
Sergey Bobryshov, Natalia Dzhegutanova
doaj
GMS Zeitschrift für Medizinische Ausbildung, 2010 [english] Objective: In order to acquire the academic title “doctor” in Germany, it is essential to complete a dissertation. A high number of publications at German universities are based on medical dissertations.
Harendza, Sigrid +6 more
doaj +1 more source
A Methodology for Developing Computational Implementations of Scientific Theories [PDF]
, 2008 “This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders.
Gobet, F., Lane, P.C.R.
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Frontiers in PsychologyOn-the-job skills match, in which employee knowledge and proficiencies (skills) are well-matched with the needs of the job, is often considered more beneficial, both for employees as well as for organizations and society, than a mismatch.
Linda Koopmans +3 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source