Results 71 to 80 of about 3,068,645 (312)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
In Honorem Academician Răzvan Theodorescu [PDF]
Codrul Cosminului, 2019 The author evokes the human and scientific dimension of the personality of Professor Razvan Theodorescu, the Vice-President of the Romanian Academy. His remarkable research results and the outstanding achievements brought his fame and recognition both ...
Vasile M. Demciuc
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Boundless and bounded interactions in the knowledge work process : the role of groupware technologies. [PDF]
, 2000 This paper considers how the time/space distanciation that the introduction of a groupware technology provided was implicated in the knowledge work process.
Hayes, Niall, Hayes, N
core +1 more source
, 2023 The International journal Scientific Work covers all fields of science.
openaire +3 more sources
ORIGINALITY - CONDITION FOR PROTECTION OF SCIENTIFIC WORKS [PDF]
Challenges of the Knowledge Society, 2014 The Doctrine defines originality as a combination of fancy, audacity, individuality and novelty. This ensemble of ideas meant to define originality appeals to the patents/ certificates Law for which novelty/ innovation is not enough.
Viorel ROŞ, Andreea LIVĂDARIU
doaj
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Connecting Scientific Data to Scientific Experiments with Provenance [PDF]
, 2007 As scientific workflows, and the data they operate on, grow in size and complexity, the task of defining how those workflows should execute (which resources they should use, where those resources should be in preparation for processing etc.) becomes ...
Mehta, G +17 more
core +1 more source
THE MEANINGS, PURPOSE AND FUNCTION OF THE CONTEMPORARY RUSSIAN GRADUATE SCHOOL: PROBLEM ANALYSIS
Вестник Северо-Кавказского федерального университета, 2022 The article deals with various aspects of understanding of the modern model of the Russian postgraduate school as a level of higher education. The scientific, normative, statistical materials and data revealing the target and functional basis of ...
Sergey Bobryshov, Natalia Dzhegutanova
doaj