Results 71 to 80 of about 20,856,203 (292)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Capturing occupational risk of airborne disease: An international job-exposure matrix based on five exposure factors

open access: yesScandinavian Journal of Work, Environment & Health
OBJECTIVE: This study aimed to construct a job-exposure matrix (JEM) for the risk of being infected by infectious agents through airborne or droplet transmission in an occupational setting, which might lead to a respiratory disease.
Karen M Oude Hengel   +8 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Manœuvrer au milieu des multiples tournants des STS

open access: yesRevue d'anthropologie des connaissances, 2023
This paper speculates on what it's like to write a call for papers for an international conference. From behind the scenes, it aims to reflect on the singular exercise of addressing a community of colleagues around a particular discipline and/or a ...
Julio Paulos, Loïc Riom
doaj   +1 more source

A Methodology for Developing Computational Implementations of Scientific Theories [PDF]

open access: yes, 2008
“This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders.
Gobet, F., Lane, P.C.R.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Links and Hubs of Scientific Information - the Case of the MTMT [PDF]

open access: yes, 2011
We present the Hungarian National Scientific Bibliography project: the MTMT. We argue that presently available commercial systems cannot be used as a comprehensive national bibliometric tool.
Holl, András, Makara, B. Gábor
core  

Good practices, innovation or scientific research in education? A conceptual reflection [PDF]

open access: yes, 2020
In this work a conceptual delimitation of "good teaching practices", "educational innovation" and "educational research" is proposed, based on both the experimental design and the quality of the evidence provided by these ...
Hernández Fernández, Antonio
core  

Does economics need a scientific revolution? [PDF]

open access: yes, 2009
Economics does not need a scientific revolution. Economics needs accurate measurements according to high standards of natural sciences and meticulous work on revealing empirical relationships between measured variables.Comment: 6 pages, 3 ...
Kitov, Ivan O.
core   +3 more sources

Distribution of authorship in a scientific work.

open access: yesArquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery, 2012
INTRODUCTION To publish became almost compulsory in Medicine. There is no doubt about the importance of publishing research, but the ordering of its authors is not easy.
A. Petroianu
semanticscholar   +1 more source

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