Results 111 to 120 of about 7,963,700 (296)
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Referencing in Scientific Writing [PDF]
openaire +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Learning philosophical thinking through collaborative writing in secondary education
This study investigated students' practice of philosophical thinking through collaborative writing in secondary education. A philosophy course was developed following the rationale of the learning communities in which writing was used as an epistemic ...
Corcelles-Seuba, Mariona +1 more
core +1 more source
CRITICAL ISSUES OF SCIENTIFIC WRITING
This study discusses the contemporary issues that usually take place in the process of scientific writing. This paper focuses on student’s perception towards scientific writing and how information technology that gives great contribution to bad behavior which is plagiarism, and how to reduce it.
openaire +3 more sources
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Creative writing and new media
Writing has always involved forms of technology, whether the pen, the typewriter or the computer. But the growth of new media technologies is offering many exciting possibilities for experimentation and innovation in creative writing.
Smith, Hazel (R11761)
core

