Results 71 to 80 of about 18,247 (232)

A case of progressive systemic scleroderma in a patient who had COVID-19: observation using computed tomography over time

Актуальные проблемы теоретической и клинической медицины
A clinical case of a patient with systemic scleroderma who underwent COVID-19. In systemic scleroderma, pulmonary involvement is the most common cause of death in patients is presented.
E. A. Akhmetov, A. N. Kensarina, А. K. Oryndybayeva   +2 more
doaj   +1 more source

Expert Perspectives: Defining and Managing Progressive Pulmonary Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Systemic sclerosis–associated interstitial lung disease (SSc‐ILD) is one of the leading causes of morbidity and mortality in SSc, affecting up to three‐quarters of patients. The disease course is highly heterogeneous, ranging from indolent, nonprogressive forms to rapidly progressive pulmonary fibrosis (PPF).
Devis Benfaremo, Dinesh Khanna, Corrado Campochiaro, Vincent Cottin, Fabrizio Luppi, Marco Matucci‐Cerinic, Gianluca Moroncini, Yannick Allanore   +7 more
wiley   +1 more source

Cutaneous Manifestations of Scleroderma and Scleroderma-Like Disorders: a Comprehensive Review

, 2017
Scleroderma refers to an autoimmune connective tissue fibrosing disease, including three different subsets: localized scleroderma, limited cutaneous systemic sclerosis, and diffuse cutaneous systemic sclerosis with divergent patterns of organ involvement,
ATZORI, LAURA, Parodi, Aurora, Giulia Gasparini, Aurora Parodi, FERRELI, CATERINA, Emanuele Cozzani, Caterina Ferreli, Gasparini, Giulia, Franco Rongioletti, RONGIOLETTI, FRANCO, Cozzani, Emanuele, Laura Atzori   +11 more
core   +1 more source

Characterization of Pulmonary Functional Abnormalities in Systemic Sclerosis Using Xenon MRI

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Xenon MRI is increasingly used to evaluate patients with interstitial lung disease (ILD) and pulmonary hypertension (PH), both of which are common manifestations of systemic sclerosis (SSc). As such, Xe‐MRI may be suited to interrogate lung function impairment in SSc.
Dawson Shaver, Steven Haworth, Evan Graumann, Bradie Frizzell, David H. Lee, Jiwoong Choi, Chase S. Hall, Scott M. Matson, Mark Hamblin, Mario Castro, Paul S. Schmidt, Peter J. Niedbalski   +11 more
wiley   +1 more source

Nail Disorders in Systemic Conditions

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail findings in children can be indicative of an underlying systemic disease. Many of these findings are seen in multiple entities and are not specific to one disease. The importance of specifically examining for these nail changes cannot be overstated.
Jane Sanders Bellet
wiley   +1 more source

Autoantibodies, cutaneous subset and immunosuppressants contribute to the cancer risk in systemic sclerosis

RMD Open
Objective Systemic sclerosis (SSc) is associated with an increased risk of cancer. We aimed to assess the prevalence of cancer in our cohort and to explore possible associations with clinical, immunological and treatment characteristics.Methods Our ...
Maria De Santis, Carlo Selmi, Angela Ceribelli, Stefanos Bonovas, Francesca Motta, Antonio Tonutti, Natasa Isailovic, Rita Ragusa, Emanuele Nappi   +8 more
doaj   +1 more source

Morphoea with Myositis: A Rare Association

Case Reports in Rheumatology, 2011
In this case, we describe an unusual presentation of a young woman with a rash typical of morphoea (confirmed on biopsy), who went on to develop myositis in an atypical distribution.
Mary Sommerlad, Richard Bull, Claire Gorman   +2 more
doaj   +1 more source

Lipodystrophy and adipose tissue recovery are mediated by the Wnt/lipogenesis axis during skin fibrosis

The Journal of Pathology, EarlyView.
Abstract Acquired lipodystrophy in the dermal white adipose tissue (DWAT) is an early phenotype of skin fibrosis, followed by the accumulation of extracellular matrix (ECM). Lipodystrophy syndromes are estimated to affect 1 in 20,000 people and are associated with metabolic comorbidities.
Suneeti R Madhavan, Piper Moore, Rohan Varshney, Miles Montegut, Qiannan Ma, Kayla Klatt, Reshmi Parameswaran, Elif G Ertugral, Chandrasekhar R Kothapalli, Michael C Rudolph, Radhika P Atit   +10 more
wiley   +1 more source

Scleroderma.

, 2009
Scleroderma (systemic sclerosis) is a complex disease in which extensive fibrosis, vascular alterations, and autoantibodies against various cellular antigens are among the principal features There are two major subgroups in the commonly accepted ...
Gabrielli A., AVVEDIMENTO, VITTORIO ENRICO, AVVEDIMENTO EV, GABRIELLI, ARMANDO, Krieg T.   +4 more
core  

Scleroderma renal crisis: poor outcome despite aggressive antihypertensive treatment

, 2003
Background: Scleroderma renal crisis (SRC) is a rare but feared complication of scleroderma. Angiotensin-­converting enzyme (ACE) inhibition has significantly improved survival, but it is unknown whether prophy­lactic ACE inhibitors will prevent this ...
Cleland, L., Ahern, Michael John, M. J. Ahern, M. Coleman, J. G. Walker, L. Cleland, M. Rischmueller, Smith, M., Smith, Malcolm Douglas, Rischmueller, M., Roberts-Thomson, P., Roberts-Thomson, Peter John, P. J. Roberts‐Thomson, Coleman, M., Pile, K., Walker, Jennifer Gauld, Coleman, Mark, M. D. Smith, K. Pile, Ahern, M., Rischmueller, Maureen, Pile, Kevin D, Cleland, Leslie G, Walker, J.   +23 more
core   +1 more source