Results 91 to 100 of about 39,410 (213)

Severe Acro-osteolysis in a Case of Limited Cutaneous Scleroderma

open access: yesIranian Journal of Public Health, 2017
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Milad HOSSEINIALHASHEMI   +2 more
doaj  

Transcriptional inhibition of type I collagen gene expression in scleroderma fibroblasts by the antineoplastic drug ecteinascidin 743. [PDF]

open access: yes, 2003
We previously showed that COL1A1 expression is up-regulated at the transcriptional level in systemic sclerosis (SSc) fibroblasts and that the CCAAT-binding factor (CBF) is involved in this increased expression.
Herrick, David J   +3 more
core   +2 more sources

Assessment of Treatment Response in Patients With Scleromyxedema by the Double Modified Rodnan Skin Score

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Scleromyxedema (SMX) is a cutaneous mucinosis characterised by an abnormal accumulation of mucin in the skin and limited treatment options. Assessment of therapy response during treatment is challenging. Objectives Patients with SMX receiving high‐dose intravenous IVIg therapy were included to assess validity of the double modified ...
Julia K. Winkler, Alexander H. Enk
wiley   +1 more source

Nintedanib for systemic sclerosis–associated interstitial lung disease [PDF]

open access: yes, 2019
BackgroundInterstitial lung disease (ILD) is a common manifestation of systemic sclerosis and a leading cause of systemic sclerosis-related death. Nintedanib, a tyrosine kinase inhibitor, has been shown to have antifibrotic and antiinflammatory effects ...
Alves, Margarida   +16 more
core   +3 more sources

Immunotherapy‐Related Cutaneous Toxicities in Melanoma: A Dermoscopic Perspective

open access: yesJEADV Clinical Practice, EarlyView.
Dermoscopy serves as a valuable tool in the everyday dermatological and oncological practice for melanoma patients, allowing for the prompt identification of immune‐related cutaneous toxicities and guiding clinicians toward appropriate therapeutic decisions.
Grażyna Kamińska‐Winciorek   +3 more
wiley   +1 more source

Review article: pathogenesis and clinical manifestations of gastrointestinal involvement in systemic sclerosis. [PDF]

open access: yes, 2017
BACKGROUND: Gastrointestinal tract (GIT) involvement is a common cause of debilitating symptoms in patients with systemic sclerosis (SSc). There are no disease modifying therapies for this condition and the treatment remains symptomatic, largely owing to
Abraham   +105 more
core   +2 more sources

Nail Disorders in Systemic Conditions

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Nail findings in children can be indicative of an underlying systemic disease. Many of these findings are seen in multiple entities and are not specific to one disease. The importance of specifically examining for these nail changes cannot be overstated.
Jane Sanders Bellet
wiley   +1 more source

Determinants of Improved Dyspnea and Exercise Tolerance With Nasal High‐Flow O2 Therapy in Fibrotic Interstitial Lung Disease: A Pilot Physiological Study

open access: yesRespirology, EarlyView.
We tested the respective effect of high‐flow and supplemental O2 from nasal high‐flow O2 therapy (NHFO2) on dyspnea and exercise tolerance in fibrotic interstitial lung disease. Supplemental O2 and NHFO2 (but not high‐flow) provided improvements in these outcomes at “iso‐O2 saturation” due to reduced ventilatory requirements.
Sarah Thivent   +4 more
wiley   +1 more source

Grundlagen und Wirkprinzipien von wassergefiltertem Infrarot A (wIRA) in Bezug zur Wundheilung [PDF]

open access: yes, 2006
The experience of the pleasant heat of the sun in moderate climatic zones arises from the filtering of the heat radiation of the sun by water vapor in the atmosphere of the earth.
Hoffmann, Gerd
core   +1 more source

Validation of the Milan Score Using Prolonged Wireless PH Monitoring

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
The Milan Score, a high‐resolution manometry‐derived tool, predicts pathological GERD on 96‐h wireless pH monitoring with high specificity and positive predictive value, maintaining robust discriminative performance across both typical and atypical symptom profiles and outperforming single HRM parameters as a standalone manometric parameter.
Stefano Siboni   +8 more
wiley   +1 more source

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