Results 41 to 50 of about 8,929 (178)

Clinical Profile of Methotrexate-resistant Juvenile Localised Scleroderma

Acta Dermato-Venereologica, 2019
Methotrexate has demonstrated its efficiency for the treatment of juvenile localized scleroderma but some patients may be resistant. The aim of our study was to define the profile of such patients.
Juliette Hardy, Franck Boralevi, Stéphanie Mallet, Natalia Cabrera, Alexandre Belot, Alice Phan, Sébastien Barbarot, Audrey Duriez-Lasek, Christine Chiaverini, Thomas Hubiche, Emmanuel Mahé, Edouard Bégon, Emmanuelle Bourrat, Olivia Boccara, Hélène Aubert, Martine Grall Lerosey, Catherine Droitcourt, Maryam Piram, Juliette Mazereeuw-Hautier, Research Group of the French Society of Paediatric Dermatology (SDFP in French)   +19 more
doaj   +1 more source

Acquired Strabismus in Linear Scleroderma of the Face

Acta Dermato-Venereologica, 2019
is missing (Short communication)
Giorgia Martini, Maria Elisabetta Zannin, Fiorella Rodeghiero, Sandro Dal Pos, Francesco Zulian   +4 more
doaj   +1 more source

Endoscopic Removal of Impacted Barium Stools Using a Snare and a Long Hood: A Rare Complication Following Upper Gastrointestinal Barium X‐ray Radiography (With Video)

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Barium sulfate is widely used as a radiographic contrast medium in upper gastrointestinal barium X‐ray radiography for cancer screening in Japan. Although generally considered safe, rare complications such as bowel obstruction due to impacted barium stools can occur.
Takaaki Kishino, Naoki Okamoto, Kohei Fukumoto   +2 more
wiley   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Progressive Hemifacial Atrophy with Morphea of Cheek

Journal of Indian Academy of Oral Medicine and Radiology, 2006
Scleroderma is a rare collagen disorder in which fibrosis of skin, subcutaneous tissues and muscles can occur with occasional involvement of bones. Localized scleroderma is a benign condition but can cause significant deformity when it affects the face ...
Ajit Auluck, Keerthilatha M Pai
doaj  

Immunopathogenesis of Pediatric Localized Scleroderma

Frontiers in Immunology, 2019
Localized scleroderma (LS) is a complex disease characterized by a mixture of inflammation and fibrosis of the skin that, especially in the pediatric population, also affects extracutaneous tissues ranging from muscle to the central nervous system ...
Kathryn S. Torok, Suzanne C. Li, Suzanne C. Li, Heidi M. Jacobe, Sarah F. Taber, Sarah F. Taber, Anne M. Stevens, Anne M. Stevens, Francesco Zulian, Theresa T. Lu, Theresa T. Lu, Theresa T. Lu   +11 more
doaj   +1 more source

Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause

Immunology, Volume 177, Issue 4, Page 736-748, April 2026.
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley   +1 more source

Clinical case of morphea associated with a malignant process with extensive skin lesions, which debuted against the background of taking anti-gouty remedy

Лечащий Врач
Background. Localized scleroderma may be associated with a malignant process occurring in the body. The onset of scleroderma does not always coincide with the onset of clinical manifestations of oncology.
P. O. Kazakova
doaj   +1 more source

A Teenage Guitarist's Swollen Fingers

JEADV Clinical Practice, EarlyView.
Maho Matsuo, Hiroaki Iwata
wiley   +1 more source

Sex Matters: Hormonal and Chromosomal Determinants of Autoimmunity and Anti‐Cancer Immunity Across the Lifespan

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Sex plays a key role in shaping both anti‐cancer immunity and autoimmunity. Biological factors underlying sexual dimorphism have now been identified in multiple aspects of anti‐cancer immunity and autoimmunity. These factors include sex differences in hormone levels, chromosome complement, and expression of the long non‐coding RNA XIST.
Christian G. Bustillos, Esther M. Peluso, Sophia L. Cha, Melissa G. Lechner, Maureen A. Su   +4 more
wiley   +1 more source