Results 131 to 140 of about 55,245 (231)

Clinicopathological Challenge: A Progressively Enlarging Hardened Skin Plaque

open access: yesInternational Journal of Dermatology, Volume 65, Issue 1, Page 15-17, January 2026.
ABSTRACT Stiff skin syndrome (SSS) is a rare connective tissue disease manifesting as a progressive, non‐inflammatory fibrosis that causes the skin and soft tissues to harden. It can result in restricted joint movement, particularly affecting the shoulder and pelvic girdle. A segmental variant with a better prognosis has been described.
Marian Fernández Martínez   +3 more
wiley   +1 more source

Working under Pressure: Scleroderma Presenting with Bilateral Exudative Retinal Detachment in the Context of Scleroderma Renal Crisis: A Case Report

open access: yesCase Reports in Ophthalmology
This is an observational case report to detail a novel case of scleroderma renal crisis presenting as bilateral exudative retinal detachments in a patient with newly diagnosed systemic sclerosis.
Rem Aziz   +3 more
doaj   +1 more source

Wearable‐Based Monitoring of Autonomic and Gastrointestinal Function in Disorders of Gut‐Brain Interaction: A Systematic Review and Meta‐Analyses

open access: yesNeurogastroenterology &Motility, Volume 38, Issue 1, January 2026.
Wearables show promise for identifying autonomic and GI dysfunction in disorders of gut–brain interaction, particularly via HRV, though further standardized studies are required to validate their clinical use. ABSTRACT Background Autonomic nervous system (ANS) activity is implicated in the pathogenesis of disorders of gut‐brain interaction (DGBI ...
Fleur Veldman   +4 more
wiley   +1 more source

Mimics of scleroderma

open access: yesIndian Journal of Rheumatology, 2017
Systemic sclerosis is a rare autoimmune connective tissue disorder characterised typically by tightening and tethering of skin. However, several other disorders are also characterised by hardening and thickening of skin.
Kaveri K Nalianda   +3 more
doaj  

Effectiveness of Punch Grafting in Promoting Healing and Reducing Pain in Hard‐to‐Heal Leg Ulcers

open access: yesWound Repair and Regeneration, Volume 34, Issue 1, January/February 2026.
ABSTRACT Approximately 20% of chronic leg ulcers remain recalcitrant despite treatment of underlying factors and best standard of wound care. This study aimed to evaluate the effectiveness of partial‐thickness punch grafting in promoting healing and reducing pain in patients with chronic, hard‐to‐heal leg ulcers of various causes. In this single‐centre,
Julia Neuenschwander   +5 more
wiley   +1 more source

Simulating Cor pulmonale in chronic obstructive pulmonary disease via cigarette smoke exposure and left pulmonary artery ligation in mice

open access: yesPhysiological Reports, Volume 14, Issue 1, January 2026.
Mice subjected to LPAL and cigarette smoke exposure exhibited COPD‐like features, including impaired lung function, emphysematous alterations, pulmonary inflammatory cell infiltration, and airway remodeling, accompanied by increased right ventricular systolic pressure, right ventricular hypertrophy, fibrosis, macrophage aggregation, and reduced ...
Xilong Wang   +9 more
wiley   +1 more source

A Case of Chronic Intestinal Pseudo-Obstruction [PDF]

open access: yes, 2012
Scleroderma is a systemic disease characterized by the deposition of excessive collagen and other matrix elements in the skin as well as in multiple internal organs.
Baichi, Matt
core   +1 more source

Nintedanib in systemic sclerosis treatment: a case report

open access: yesJournal of Medical Case Reports
Background Nintedanib was approved for the treatment of scleroderma and scleroderma-related interstitial lung disease, as it decrease the forced expiratory volume. Case presentation A 48-year-old Asian female patient with systemic scleroderma 6 years ago
Maysoun Kudsi   +2 more
doaj   +1 more source

Band Acro-Osteolysis as a Less Common Radiologic Pattern in Systemic Scleroderma: A Case Report. [PDF]

open access: yesClin Med Insights Case Rep
Khezri S   +4 more
europepmc   +1 more source

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