Results 191 to 200 of about 122,915 (346)
Pulmonary Circulation, Volume 16, Issue 1, January 2026.ABSTRACT The proliferation of pulmonary artery smooth muscle cells (PASMCs) is a key mechanism in hypoxic pulmonary hypertension (HPH). Resistin‐like Molecule Beta (RELM‐β) promotes the hypoxia‐induced proliferation of PASMCs, and calcium ions (Ca²⁺) play an important role in cell proliferation. However, the mechanism by which RELM‐β regulates Ca²⁺ and
Guoyu Liu +5 more
wiley +1 more source
Respirology Case Reports, Volume 14, Issue 1, January 2026.We report the case of a patient with anti‐eIF2B‐positive SSc‐ILD managed with stepwise mycophenolate titration and subsequent nintedanib addition, accompanied by serial biomarkers and clinical follow‐up to help delineate the therapeutic course within this rare serological phenotype.
Hiro Ikeda +3 more
wiley +1 more source
PDE-5 Inhibitors in Scleroderma Raynaud Phenomenon and Digital Ulcers: Current Status of Clinical Trials [PDF]
, 2011 Ann Impens +2 more
openalex +1 more source
The Journal of Dermatology, Volume 53, Issue 1, Page 41-53, January 2026.ABSTRACT Systemic sclerosis is an autoimmune disease characterized by vasculopathy, fibrosis, and immune dysregulation. Anti‐SS‐A antibodies (anti‐SSA) have been reported to confer severe clinical manifestations in some Western and Japanese cohorts. We aimed to determine whether anti‐SSA seropositivity affects clinical outcomes in Japanese patients. We
Nana Ishida +4 more
wiley +1 more source
Esomeprazole inhibits proliferation of scleroderma fibroblasts via cell cycle regulation. [PDF]
Front PharmacolKhan MA +9 more
europepmc +1 more source
A Patient with Localized Scleroderma Successfully Treated with Etretinate [PDF]
, 2014 Tomoko Shima +3 more
openalex +1 more source
A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered ‘early’?
European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Elvis Hysa +7 more
wiley +1 more source
Association of <i>MMP9</i> and <i>NOS3</i> Polymorphisms with Distinct Clinical Forms of Juvenile Scleroderma and Characteristics of Humoral Immunity. [PDF]
Int J Mol SciOsminina M +13 more
europepmc +1 more source