Results 61 to 70 of about 11,032 (258)

A prospective observational study of mycophenolate mofetil treatment in progressive diffuse cutaneous systemic sclerosis of recent onset. [PDF]

, 2012
OBJECTIVE: A prospective observational study of mycophenolate mofetil (MMF) treatment in patients with diffuse progressive cutaneous systemic sclerosis (SSc) of recent onset.
Jimenez, Sergio A., Lee, MD, Jason B., Mendoza, MD, Fabian A., Nagle, Sarah J.   +3 more
core   +3 more sources

Evaluation of estimated glomerular filtration rate and clinical variables in systemic sclerosis patients [PDF]

, 2016
Objectives: The most important renal complication of systemic sclerosis (SSc) is scleroderma renal crisis (SRC). Many patients demonstrate less severe renal complications, most likely associated with reduced renal blood flow and a consequent reduction in
Amoroso, Antonio, Barbano, Biagio, Cianci, Rosario, Gigante, Antonietta, Granata, Guido, Quarta, Silvia, Rosato, Edoardo, Salsano, Felice   +7 more
core   +1 more source

Stimulation of endothelin-1 production by autoantibodies present in patients with scleroderma renal crisis

Clinical Immunology
Pinchao Wang, Dashan Wu, Zexian Gong, Michael Adu Gyamfi, Julian Kamhieh‐Milz, Dennyson Fonseca, Gülistan Sürücü, Muhammad Imtiaz Ashraf, Harald Heidecke, D Sikorska, Otávio Cabral-Marques, Guido Moll, Gabriela Riemekasten, Janusz Witowski, Rusan Catar   +14 more
openalex   +2 more sources

Systemic sclerosis with renal crisis and pericardial effusion

Clinical Case Reports, 2020
Scleroderma renal crisis occurs in 10% of patients with systemic sclerosis carrying a poor prognosis. A kidney biopsy is consistent with thrombotic microangiopathy (TMA) with clinical findings discerning it from other TMAs.
Kalyan Prudhvi, Jayasree Jonnadula, Gurusaravanan Kutti Sridharan, Mary Dominguez   +3 more
doaj   +1 more source

Intrarenal arterial stiffness is increased in systemic sclerosis patients with anti-ribonucleic acid polymerase III antibodies [PDF]

, 2017
N
Afeltra, Antonella M. Vittoria, Barbano, Biagio, Cianci, Rosario, Gigante, Antonietta, Margiotta, Domenico, Navarini, Luca, Rosato, Edoardo   +6 more
core   +1 more source

Advances in pathogenesis and treatment of systemic sclerosis [PDF]

, 2015
Systemic sclerosis is the most severe disease within the scleroderma spectrum and is a major medical challenge with high mortality and morbidity.
Denton, CP
core   +2 more sources

Atypical rapid onset Scleroderma Renal Crisis (SRC) complicated with diffuse alveolar hemorrhage and pleuro-pericardial effusions in a patient with recently diagnosed breast cancer and a positive anti-RNA polymerase III Ab.: A case report

Respiratory Medicine Case Reports, 2018
Scleroderma associated Pulmonary–Renal Syndrome is a rare but severe complication with a poor prognosis and high mortality. A high index of suspicion is needed for early recognition of this potential complication in patients with systemic sclerosis and ...
Hazim Bukamur, Obadah Aqtash, Ibrahim Shahoub, Emhemmid Karem, Iheanyichukwu Ogu, Fuad Zeid   +5 more
doaj   +1 more source

Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: A new potential target for antifibrotic therapy [PDF]

, 2018
Background: Fibrosis may be considered the hallmark of systemic sclerosis (SSc), the end stage triggered by different pathological events. Transforming growth factor-β (TGF-β) and platelet-derived growth factor BB (PDGF-BB) are profibrotic molecules ...
Berardicurti O., Carubbi F., Ciccia F., Cipriani P., Di Bartolomeo S., Di Benedetto P., Giacomelli R., Guggino G., Liakouli V., Panzera N., Ruscitti P., Triolo G.   +11 more
core   +1 more source

Patterns of renal pathology in Chinese patients with systemic sclerosis undergoing renal biopsy at a tertiary medical center

Journal of International Medical Research, 2020
Objective We investigated renal injury characteristics in Chinese patients with systemic sclerosis (SSc) who had undergone renal biopsy. Methods We searched the medical records of patients with SSc who were hospitalized at Peking Union Medical College ...
Xiao-yu Cao, He Liu, Dong Xu, Meng-tao Li, Qian Wang, Li Jiang, Yong Hou, Li-xiu Zhu, Xiao-feng Zeng   +8 more
doaj   +1 more source

Registry of the Spanish network for systemic sclerosis: Survival, prognostic factors, and causes of death [PDF]

, 2015
Simeón-Aznar, C.P., Fonollosa-Plá, V., Tolosa-Vilella, C., Espinosa-Garriga, G., Campillo-Grau, M., Ramos-Casals, M., García-Hernández, F.J., Castillo-Palma, M.J., Sánchez-Román, J., Callejas-Rubio, J.L., Ortego-Centeno, N., Egurbide-Arberas, M.V ...
Caminal Montero, Luis, Fonollosa-Plá, V., Simeón Aznar, Carmen Pilar, Tolosa-Vilella, C., Trapiella Martínez, Luis   +4 more
core   +2 more sources