Results 1 to 10 of about 562 (139)

Scleromyxedema Managed With High-Dose Intravenous Immunoglobulin and Bortezomib–Dexamethasone: A Case Report [PDF]

Case Reports in Oncological Medicine
Scleromyxedema is a rare, chronic cutaneous mucinosis marked by widespread waxy papules and potential extracutaneous involvement. This case report discusses the management of a 48-year-old female diagnosed with scleromyxedema, who initially partially ...
Darren Wijaya, Zachary Hanson, Eric K. Lau, Mojtaba Akhtari   +3 more
doaj   +3 more sources

Monoclonal Gammopathies of Clinical Significance—Scleromyxedema: A Case Report and Literature Review [PDF]

Clinical Case Reports
Scleromyxedema is an uncommon, chronic connective tissue disorder with an obscure etiology. It is distinguished by fibromyxoid skin lesions and elevated serum monoclonal immunoglobulin levels.
Shanshan Liang, Jingjing Zeng, Peiying Zhong, Chengyao Jia, Li Zhang   +4 more
doaj   +3 more sources

Skin‐Colored Papules on the Face and Chest of a Female Patient [PDF]

Clinical Case Reports
Scleromyxedema is an unpredictable but progressive disease and can be lethal due to systemic involvement if not diagnosed timely. Hence, we require a keen observational clinical eye to diagnose the condition from its differentials, along with further ...
Mehdi Ghahartars, Seyyede Zeinab Azimi, Mojgan Akbarzadeh Jahromi, Mohammad Reza Namazi   +3 more
doaj   +3 more sources

Case report: Scleromyxedema associated with a monoclonal gammapathy: Successful treatment with intravenous immunoglobulins [PDF]

Frontiers in Immunology, 2023
Scleromyxedema is a rare idiopathic fibromucinous disorder characterized by a generalized papular and sclerodermoid cutaneous eruption. Patients often have praraproteinemia and extracutaneous, even lethal, manifestations.
Shang-shang Wang, Qin-yi Chen, Lei-hong Xiang   +2 more
exaly   +4 more sources

Dermato-Neuro Syndrome After Intravenous Immunoglobulin Infusion: Case Report [PDF]

Reports
Background and Clinical Significance: Dermato-neuro syndrome is a rare, potentially fatal complication of scleromyxedema, characterized by a prodrome of flu-like symptoms, and a triad of fever, confusion, and seizures.
Bryce Kassalow, Soha Kazmi, Said Shukri, Zachary N. London   +3 more
doaj   +2 more sources

Unusual Cutaneous Manifestations in a Patient with a History of Hepatitis B: A Case of Scleromyxedema and Literature Review [PDF]

Clinical, Cosmetic and Investigational Dermatology
Aili Gao, Xin Tian, Dexiu Lang, Yue Chen Department of Dermatology, Guangzhou Dermatology Hospital, Guangzhou, Guangdong, People’s Republic of ChinaCorrespondence: Yue Chen, Department of Dermatology, Guangzhou Dermatology Hospital, Guangzhou, People’s ...
Gao A, Tian X, Lang D, Chen Y
exaly   +4 more sources

Dupilumab improves itch, but not fibrosis, in a patient with scleromyxedema: A case report [PDF]

SAGE Open Medical Case Reports
Scleromyxedema is a rare, chronic mucinosis characterized by widespread skin fibrosis and an associated monoclonal gammopathy. Therapeutic options remain limited.
Katya Peri, Naila Bouadi, Anna Nikonova, Ivan V. Litvinov, Elena Netchiporouk   +4 more
doaj   +2 more sources

Scleredema Associated With IgG/κ Monoclonal Gammopathy of Clinical Significance Successfully Treated With Daratumumab Monotherapy: A Case Report. [PDF]

EJHaem
ABSTRACT Background Cutaneous monoclonal gammopathy of clinical significance (MGCS) is rare and may present with scleredema‐like fibrosing skin disease. Case A 59‐year‐old man developed progressive induration of the upper body. Laboratory studies revealed an IgG/κ monoclonal protein, and skin biopsy showed dermal thickening with mucin deposition.
Marcolongo D, Bressan A, Zanatta E, Alaibac MSA, Gianesello I, Binotto G, Pavan L, Tos APD, Trentin L, Vianello F.   +9 more
europepmc   +2 more sources

Cutaneous Focal Mucinosis Successfully Treated With Superpulsed Carbon Dioxide Laser. [PDF]

Case Rep Med
Cutaneous focal mucinosis (CFM) is a rare dermatological condition characterized by localized mucin deposition in the dermis, presenting as solitary or multiple asymptomatic papules or nodules. Treatment options are limited, with spontaneous resolution occurring in some cases, while others persist or require intervention.
Hekmat M, Hosseini A, Shirazi Yeganeh B, Fazelzadeh Haghighi N.   +3 more
europepmc   +2 more sources

Sclerosing diseases of the skin. [PDF]

J Dtsch Dermatol Ges
Summary Sclerosing skin diseases comprise a group of distinct dermatological conditions characterized by fibrotic changes that may severely impair patients’ quality of life. These conditions often present with cutaneous manifestations and, in some cases, may extend to extracutaneous tissues, potentially resulting in significant morbidity and mortality.
Kalantari Y, Meier K, Ghoreschi K, Kinberger M, Solimani F.   +4 more
europepmc   +2 more sources