Hyalase in Dermatology: Applications Beyond Filler Management. [PDF]
ABSTRACT Background Hyaluronic acid (HA) is a key extracellular matrix component in the skin. Hyaluronidase is an enzyme that breaks down HA into monosaccharides. The FDA has approved this enzyme for hypodermoclysis, drug absorption enhancement, and subcutaneous urography.
Hasanzadeh S +6 more
europepmc +2 more sources
Granulomatous variant of scleromyxedema successfully treated with topical ruxolitinib, dapsone and intravenous immunoglobulin [PDF]
Donglin Zhang, BA +5 more
doaj +2 more sources
Clonal disorders of clinical significance. A concept with important therapeutic implications. [PDF]
Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 5, Page 891-892, May 2025.
Lipsker D.
europepmc +2 more sources
Successful treatment of scleromyxedema with dupilumab: A case report [PDF]
Abdulelah Alghamdi, MBBS +4 more
doaj +2 more sources
Paraneoplastic atypical scleromyxedema with advanced gastric cancer
Se Jin Oh, Jong Hee Lee, Seung Hwan Oh
exaly +3 more sources
To synthesize the current known data on pathogenesis and treatment of scleromyxedema. This review will also highlight the clinical presentation, systemic features and outcomes and distinguishing features between scleromyxedema and scleroderma, as a common mimic.Most recent publications have focused on describing treatment responses with novel therapies,
Bogner, Ryan R. +2 more
openaire +5 more sources
Plasma cell-directed therapies induce profound clinical and durable responses in patients with severe or relapsed/refractory scleromyxedema. [PDF]
In severe forms of monoclonal gammapathy associated with scleromyxoedema with dermatoneuro syndrome and/or cardiac involvement, deep and durable responses allowing IVIG withdrawal could be achieved using anti‐plasma cell therapy, including Imids, anti‐CD38 or proteasome inhibitors. Abstract Background Scleromyxedema (SM) is a rare skin disorder related
Theves F +12 more
europepmc +2 more sources
Scleromyxedema Without Monoclonal Gammopathy Treated with Intravenous Immunoglobulins [PDF]
Scleromyxedema is a generalized cutaneous mucinosis that may cause internal damage. This condition is frequently associated with monoclonal gammopathy. However, its physiopathological implications remains uncertain.
Letzelter, Mathilde, Grimaux, Xavier
core +2 more sources
Lichen myxedematosus: a rare group of cutaneous mucinosis [PDF]
: Cutaneous mucinoses are a heterogeneous group of dermatoses in which excess deposition of mucin in the dermis gives the skin a waxy appearance, with papules and plaques that can vary from self-healing mucinosis to even disrupting the normal shape of a ...
Ramiro Eugenio Cárdenas-Gonzalez +2 more
doaj +2 more sources
Localized eruption of glabella and eyebrows [PDF]
Celestina Okoye, MD +2 more
doaj +2 more sources

